Recent advances of organ-on-a-chip in cancer modeling research
X Liu, Q Su, X Zhang, W Yang, J Ning, K Jia, J **n, H Li… - Biosensors, 2022 - mdpi.com
Although many studies have focused on oncology and therapeutics in cancer, cancer
remains one of the leading causes of death worldwide. Due to the unclear molecular …
remains one of the leading causes of death worldwide. Due to the unclear molecular …
Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: Multilayered cross-talks in the setting of coinfections and comorbidities
The Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to healthcare …
Coronavirus 2 (SARS-CoV-2) and its sublineages pose a new challenge to healthcare …
3D tissue-engineered vascular drug screening platforms: promise and considerations
I Marei, T Abu Samaan, MA Al-Quradaghi… - Frontiers in …, 2022 - frontiersin.org
Despite the efforts devoted to drug discovery and development, the number of new drug
approvals have been decreasing. Specifically, cardiovascular developments have been …
approvals have been decreasing. Specifically, cardiovascular developments have been …
Engineering Organ-on-a-Chip Systems for Vascular Diseases
Vascular diseases, such as atherosclerosis and thrombosis, are major causes of morbidity
and mortality worldwide. Traditional in vitro models for studying vascular diseases have …
and mortality worldwide. Traditional in vitro models for studying vascular diseases have …
An organ-on-chip model of pulmonary arterial hypertension identifies a BMPR2-SOX17-prostacyclin signalling axis
Pulmonary arterial hypertension (PAH) is an unmet clinical need. The lack of models of
human disease is a key obstacle to drug development. We present a biomimetic model of …
human disease is a key obstacle to drug development. We present a biomimetic model of …
Rebuilding the Vascular Network: In vivo and in vitro Approaches
As the material transportation system of the human body, the vascular network carries the
transportation of materials and nutrients. Currently, the construction of functional …
transportation of materials and nutrients. Currently, the construction of functional …
The Role of Bone Morphogenetic Protein Receptor Type 2 (BMPR2) and the Prospects of Utilizing Induced Pluripotent Stem Cells (iPSCs) in Pulmonary Arterial …
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by increased
pulmonary vascular resistance (PVR), causing right ventricular hypertrophy and ultimately …
pulmonary vascular resistance (PVR), causing right ventricular hypertrophy and ultimately …
Recent advances in lung-on-a-chip technology for modeling respiratory disease
Tissue engineering approaches, including those to functional lung tissues, are finely honed
by the inclusion of upgraded devices that mimic biophysical and biochemical features in …
by the inclusion of upgraded devices that mimic biophysical and biochemical features in …
A Vascular Graft On‐a‐Chip Platform for Assessing the Thrombogenicity of Vascular Prosthesis and Coatings with Tuneable Flow and Surface Conditions
Vascular grafts are essential for the management of cardiovascular disease. However, the
lifesaving potential of these devices is undermined by thrombosis arising from material and …
lifesaving potential of these devices is undermined by thrombosis arising from material and …
[HTML][HTML] The role of endothelial cells in pulmonary hypertension: old concepts and new science
Endothelial dysfunction plays a key role in the initiation and progression of pulmonary
hypertension (PH), a fatal and currently incurable disease associated with increased …
hypertension (PH), a fatal and currently incurable disease associated with increased …