How cells fuse
Cell–cell fusion remains the least understood type of membrane fusion process. However,
the last few years have brought about major advances in understanding fusion between …
the last few years have brought about major advances in understanding fusion between …
The hallmarks of cell-cell fusion
Cell-cell fusion is essential for fertilization and organ development. Dedicated proteins
known as fusogens are responsible for mediating membrane fusion. However, until recently …
known as fusogens are responsible for mediating membrane fusion. However, until recently …
Membrane fusion
W Wickner, R Schekman - Nature structural & molecular biology, 2008 - nature.com
Subcellular compartmentalization, cell growth, hormone secretion and neurotransmission
require rapid, targeted, and regulated membrane fusion. Fusion entails extensive lipid …
require rapid, targeted, and regulated membrane fusion. Fusion entails extensive lipid …
Genetic basis of cell–cell fusion mechanisms
PS Aguilar, MK Baylies, A Fleissner, L Helming… - Trends in Genetics, 2013 - cell.com
Cell–cell fusion in sexually reproducing organisms is a mechanism to merge gamete
genomes and, in multicellular organisms, it is a strategy to sculpt organs, such as muscle …
genomes and, in multicellular organisms, it is a strategy to sculpt organs, such as muscle …
Unveiling the mechanisms of cell-cell fusion
EH Chen, EN Olson - Science, 2005 - science.org
Cell-cell fusion is fundamental to the development and physiology of multicellular
organisms, but little is known of its mechanistic underpinnings. Recent studies have …
organisms, but little is known of its mechanistic underpinnings. Recent studies have …
The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes
The cellular and molecular mechanisms that underlie species-specific membrane fusion
between male and female gametes remain largely unknown. Here, by use of gene discovery …
between male and female gametes remain largely unknown. Here, by use of gene discovery …
Distinct innate immune responses to infection and wounding in the C. elegans epidermis
N Pujol, S Cypowyj, K Ziegler, A Millet, A Astrain… - Current Biology, 2008 - cell.com
Background In many animals, the epidermis is in permanent contact with the environment
and represents a first line of defense against pathogens and injury. Infection of the …
and represents a first line of defense against pathogens and injury. Infection of the …
Virus and cell fusion mechanisms
B Podbilewicz - Annual review of cell and developmental …, 2014 - annualreviews.org
In biomembrane fusion pathways, membranes are destabilized through insertions of
amphipathic protein segments, lipid reorganization via hemifusion, protein restructuring, and …
amphipathic protein segments, lipid reorganization via hemifusion, protein restructuring, and …
[HTML][HTML] Cell–cell fusion
EH Chen, E Grote, W Mohler, A Vignery - FEBS letters, 2007 - Elsevier
Cell–cell fusion is a highly regulated and dramatic cellular event that is required for
development and homeostasis. Fusion may also play a role in the development of cancer …
development and homeostasis. Fusion may also play a role in the development of cancer …
Structural basis of eukaryotic cell-cell fusion
J Perez-Vargas, T Krey, C Valansi, O Avinoam… - Cell, 2014 - cell.com
Cell-cell fusion proteins are essential in development. Here we show that the C. elegans cell-
cell fusion protein EFF-1 is structurally homologous to viral class II fusion proteins. The 2.6 Å …
cell fusion protein EFF-1 is structurally homologous to viral class II fusion proteins. The 2.6 Å …