Horizontal gene transfer in archaea—from mechanisms to genome evolution
U Gophna, N Altman-Price - Annual Review of Microbiology, 2022 - annualreviews.org
Archaea remains the least-studied and least-characterized domain of life despite its
significance not just to the ecology of our planet but also to the evolution of eukaryotes. It is …
significance not just to the ecology of our planet but also to the evolution of eukaryotes. It is …
DNA repair in the archaea—an emerging picture
There has long been a fascination in the DNA repair pathways of archaea, for two main
reasons. Firstly, many archaea inhabit extreme environments where the rate of physical …
reasons. Firstly, many archaea inhabit extreme environments where the rate of physical …
Inteins in science: evolution to application
Inteins are mobile genetic elements that apply standard enzymatic strategies to excise
themselves post-translationally from the precursor protein via protein splicing. Since their …
themselves post-translationally from the precursor protein via protein splicing. Since their …
Adaptive Gene Content and Allele Distribution Variations in the Wild and Domesticated Populations of Saccharomyces cerevisiae
Recent studies on population genomics of Saccharomyces cerevisiae have substantially
improved our understanding of the genetic diversity and domestication history of the yeast …
improved our understanding of the genetic diversity and domestication history of the yeast …
Intein splicing efficiency and RadA levels can control the mode of archaeal DNA replication
Inteins (intervening proteins), mobile genetic elements removed through protein splicing,
often interrupt proteins required for DNA replication, recombination, and repair. An …
often interrupt proteins required for DNA replication, recombination, and repair. An …
Haloferax volcanii—a model archaeon for studying DNA replication and repair
P Pérez-Arnaiz, A Dattani, V Smith… - Open Biology, 2020 - royalsocietypublishing.org
The tree of life shows the relationship between all organisms based on their common
ancestry. Until 1977, it comprised two major branches: prokaryotes and eukaryotes. Work by …
ancestry. Until 1977, it comprised two major branches: prokaryotes and eukaryotes. Work by …
Protein splicing of a recombinase intein induced by ssDNA and DNA damage
Inteins (or protein introns) autocatalytically excise themselves through protein splicing. We
challenge the long-considered notion that inteins are merely molecular parasites and posit …
challenge the long-considered notion that inteins are merely molecular parasites and posit …
Genomic Instability Evolutionary Footprints on Human Health: Driving Forces or Side Effects?
In this work, we propose a comprehensive perspective on genomic instability comprising not
only the accumulation of mutations but also telomeric shortening, epigenetic alterations and …
only the accumulation of mutations but also telomeric shortening, epigenetic alterations and …
The patchy distribution of restriction–modification system genes and the conservation of orphan methyltransferases in halobacteria
Restriction–modification (RM) systems in bacteria are implicated in multiple biological roles
ranging from defense against parasitic genetic elements, to selfish addiction cassettes, and …
ranging from defense against parasitic genetic elements, to selfish addiction cassettes, and …
Conditional DnaB protein splicing is reversibly inhibited by zinc in mycobacteria
D Woods, S Vangaveti, I Egbanum, AM Sweeney, Z Li… - MBio, 2020 - Am Soc Microbiol
Inteins, as posttranslational regulatory elements, can tune protein function to environmental
changes by conditional protein splicing (CPS). Translated as subdomains interrupting host …
changes by conditional protein splicing (CPS). Translated as subdomains interrupting host …