Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …

Following prolonged neglect during the formative decades of behavioural neurology, the
temporopolar region has become a site of vibrant research on the neurobiology of cognition …

Primary progressive aphasia is a neurodegenerative disease that selectively impairs
language without equivalent impairment of speech, memory or comportment. In 118 …

Frontotemporal dementia comprises a group of clinical syndromes that are characterised by
progressive changes in behaviour, executive function, or language. The term frontotemporal …

Introduction Primary progressive aphasia (PPA) is divided into three prototypical subtypes
that are all characterized by their single core symptom of aphasia. Although later in their …

Here, we review recent progress in the diagnosis and management of primary progressive
aphasia—the language-led dementias. We pose six key unanswered questions that …

This article examines the evolution in understanding of frontotemporal dementia (FTD)
during the last four decades. A central theme is the recognition of heterogeneity. Originally …

Degraded semantic memory is a prominent feature of frontotemporal dementia (FTD). It is
classically associated with semantic dementia and anterior temporal lobe (ATL) atrophy, but …

Focal anterior temporal lobe degeneration often preferentially affects the left or right
hemisphere. While patients with left-predominant anterior temporal lobe atrophy show …

There is a longstanding ambiguity regarding the clinical diagnosis of dementia syndromes
predominantly targeting executive functions versus behaviour and personality. This is due to …