Quaternary ammonium salts and their antimicrobial potential: targets or nonspecific interactions?
M Tischer, G Pradel, K Ohlsen, U Holzgrabe - ChemMedChem, 2012 - Wiley Online Library
For more than 50 years dequalinium chloride has been used successfully as an antiseptic
drug and disinfectant, particularly for clinical purposes. Given the success of dequalinium …
drug and disinfectant, particularly for clinical purposes. Given the success of dequalinium …
Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development
M Schlitzer - ChemMedChem: Chemistry Enabling Drug …, 2007 - Wiley Online Library
Since ancient times, humankind has had to struggle against the persistent onslaught of
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …
Ecotoxicity analysis of cholinium-based ionic liquids to Vibrio fischeri marine bacteria
Cholinium-based ionic liquids are quaternary ammonium salts with a wide range of potential
industrial applications. Based on the fact that the cholinium is a complex B vitamin and …
industrial applications. Based on the fact that the cholinium is a complex B vitamin and …
Choline‐derivative‐based ionic liquids
J Pernak, A Syguda, I Mirska, A Pernak… - … A European Journal, 2007 - Wiley Online Library
A total of sixty‐three choline derivative‐based ionic liquids in the forms of chlorides,
acesulfamates, and bis (trifluoromethylsulfonyl) imides have been prepared and their …
acesulfamates, and bis (trifluoromethylsulfonyl) imides have been prepared and their …
Recent advances in antimalarial drug development
Malaria caused by protozoa of the genus Plasmodium, because of its prevalence, virulence,
and drug resistance, is the most serious and widespread parasitic disease encountered by …
and drug resistance, is the most serious and widespread parasitic disease encountered by …
Synthesis of thiazolium-labeled 1, 3, 4-oxadiazole thioethers as prospective antimicrobials: In vitro and in vivo bioactivity and mechanism of action
MW Wang, HH Zhu, PY Wang, D Zeng… - Journal of agricultural …, 2019 - ACS Publications
In this study, a type of thiazolium-labeled 1, 3, 4-oxadiazole thioether bridged by diverse
alkyl chain lengths was constructed. The antimicrobial activity of the fabricated thioether …
alkyl chain lengths was constructed. The antimicrobial activity of the fabricated thioether …
Targeting the lipid metabolic pathways for the treatment of malaria
C Ben Mamoun, ST Prigge… - Drug development …, 2010 - Wiley Online Library
The control and eventual eradication of human malaria is considered one of the most
important global public health goals of the 21st Century. Malaria, caused by intraerythrocytic …
important global public health goals of the 21st Century. Malaria, caused by intraerythrocytic …
Recent updates in the discovery and development of novel antimalarial drug candidates
Though morbidity and mortality due to malaria have declined in the last 15 years, emerging
resistance to first-line artemisinin-based antimalarials, absence of efficacious vaccines and …
resistance to first-line artemisinin-based antimalarials, absence of efficacious vaccines and …
Recent highlights in antimalarial drug resistance and chemotherapy research
This review summarizes recent investigations into antimalarial drug resistance and
chemotherapy, including reports of some of the many exciting talks and posters on this topic …
chemotherapy, including reports of some of the many exciting talks and posters on this topic …
The regioselective synthesis of 2, 5-and 4, 5-disubstituted thiazoles via the cyclization of 2-oxo-2-(amino) ethanedithioates with isocyanides
KR Singh, C Santhosh, TR Swaroop… - Organic & Biomolecular …, 2022 - pubs.rsc.org
The regioselective synthesis of 2-(methylthio)-N-aryl/alkylthiazole-5-carboxamides and ethyl-
5-(aryl/alkyl carbamoyl) thiazole-4-carboxylates was carried out via the base-induced …
5-(aryl/alkyl carbamoyl) thiazole-4-carboxylates was carried out via the base-induced …