Background Our understanding of the global scale of Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) infection remains incomplete: Routine surveillance data …

Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Background Real-world evidence supporting vaccination against COVID-19 in individuals
who have recovered from a previous SARS-CoV-2 infection is sparse. We aimed to …

Antibody responses are an important part of immunity after Coronavirus Disease 2019
(COVID-19) vaccination. However, antibody trajectories and the associated duration of …

Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been
elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 …

Molecular mimicry between viral antigens and host proteins can produce cross-reacting
antibodies leading to autoimmunity. The coronavirus SARS-CoV-2 causes COVID-19, a …

Background The level of protection after a SARS-CoV-2 infection against reinfection and
COVID-19 disease remains important with much of the world still unvaccinated. Methods …

Following primary SARS-CoV-2 vaccination, whether boosters or breakthrough infections
provide greater protection against SARS-CoV-2 infection is incompletely understood. Here …

Summary Infection with SARS‐CoV‐2, the etiology of the ongoing COVID‐19 pandemic, has
resulted in over 450 million cases with more than 6 million deaths worldwide, causing global …

Background Hydroxychloroquine (HCQ) has proved ineffective in treating patients
hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its …