Microbial degradation of steroid sex hormones: implications for environmental and ecological studies

YR Chiang, STS Wei, PH Wang, PH Wu… - Microbial …, 2020 - Wiley Online Library
Steroid hormones modulate development, reproduction and communication in eukaryotes.
The widespread occurrence and persistence of steroid hormones have attracted public …

[HTML][HTML] Modeling approaches for probing cross-feeding interactions in the human gut microbiome

P Saa, A Urrutia, C Silva-Andrade, AJ Martín… - Computational and …, 2022 - Elsevier
Microbial communities perform emergent activities that are essentially different from those
carried by their individual members. The gut microbiome and its metabolites have a …

Isolation and identification of 17β-estradiol degrading bacteria and its degradation pathway

Q Zhang, C Xue, G Owens, Z Chen - Journal of Hazardous Materials, 2022 - Elsevier
The widespread presence of 17β-estradiol (E2) in the environment is an emerging problem
because it poses a potential threat to human health and aquatic organisms. In this study, a …

Delineation of steroid-degrading microorganisms through comparative genomic analysis

LH Bergstrand, E Cardenas, J Holert, JD Van Hamme… - MBio, 2016 - Am Soc Microbiol
Steroids are ubiquitous in natural environments and are a significant growth substrate for
microorganisms. Microbial steroid metabolism is also important for some pathogens and for …

Metagenomes reveal global distribution of bacterial steroid catabolism in natural, engineered, and host environments

J Holert, E Cardenas, LH Bergstrand, E Zaikova… - MBio, 2018 - Am Soc Microbiol
Steroids are abundant growth substrates for bacteria in natural, engineered, and host-
associated environments. This study analyzed the distribution of the aerobic 9, 10-seco …

Steroids as environmental compounds recalcitrant to degradation: genetic mechanisms of bacterial biodegradation pathways

ER Olivera, JM Luengo - Genes, 2019 - mdpi.com
Steroids are perhydro-1, 2-cyclopentanophenanthrene derivatives that are almost
exclusively synthesised by eukaryotic organisms. Since the start of the Anthropocene, the …

Biotransformation kinetics and pathways of typical synthetic progestins in soil microcosms

X Jiang, Z Xue, W Chen, M Xu, H Liu, J Liang… - Journal of Hazardous …, 2023 - Elsevier
Abstract Gestodene (GES), altrenogest (ALT), and medroxyprogesterone acetate (MPA) are
three potent synthetic progestins detected in agricultural soils; however, their …

Degradation of bile acids by soil and water bacteria

FM Feller, J Holert, O Yücel, B Philipp - Microorganisms, 2021 - mdpi.com
Bile acids are surface-active steroid compounds with a C5 carboxylic side chain at the
steroid nucleus. They are produced by vertebrates, mainly functioning as emulsifiers for …

A patchwork pathway for oxygenase‐independent degradation of side chain containing steroids

M Warnke, C Jacoby, T Jung, M Agne… - Environmental …, 2017 - Wiley Online Library
The denitrifying betaproteobacterium Sterolibacterium denitrificans serves as model
organism for studying the oxygen‐independent degradation of cholesterol. Here, we …

Identification of bypass reactions leading to the formation of one central steroid degradation intermediate in metabolism of different bile salts in Pseudomonas sp …

J Holert, O Yücel, N Jagmann, A Prestel… - Environmental …, 2016 - Wiley Online Library
The bile salts cholate, deoxycholate, chenodeoxycholate and lithocholate are released from
vertebrates into soil and water where environmental bacteria degrade these widespread …