Porphyrin molecules are a widely exploited biochemical moiety, with uses in medicinal
chemistry, sensing and materials science. The shape of porphyrins, as an aromatic unit, is …

Porphyrins are variously substituted tetrapyrrolic macrocycles, with wide-ranging biological
and chemical applications derived from metal chelation in the core and the 18π aromatic …

The intrinsic challenge of large molecules to cross the cell membrane and reach intracellular
targets is a major obstacle for the development of new medicines. We report how rotation …

Porphyrin atropisomerism, which arises from restricted σ‐bond rotation between the
macrocycle and a sufficiently bulky substituent, was identified in 1969 by Gottwald and …

Chirality is one of the key factors affecting the medicinal efficacy of compounds. In addition to
central chirality, sterically hindered chiral axes commonly appear in drugs and the resulting …

The study of supramolecular self-assembly dynamics and the chirality transfer mechanism is
of importance to the rational design of potentially functional chiral supramolecular materials …

The determination of molecular stereochemistry and absolute configuration is an important
part of modern chemistry, pharmacology, and biology. Electronic circular dichroism (ECD) …

Symmetry and shape are essential aspects of molecular structure and how we interpret
molecules and their properties. We, as chemists, are comfortable with pictorial …

Inspired by the rigidified architecture of 'picket‐fence'systems, we propose a strategy utilizing
strain to impose intramolecular tension in already peripherally overcrowded structures …

Atropisomerism has been studied in many research fields; however, it is rarely studied in
organic semiconductors. In this work, we report a series of room-temperature-stable …