Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

M Yuan, B Yang, G Rothschild, JJ Mann… - Signal transduction and …, 2023‏ - nature.com
Major depressive disorder (MDD) is a chronic, generally episodic and debilitating disease
that affects an estimated 300 million people worldwide, but its pathogenesis is poorly …

[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders

MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020‏ - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

[HTML][HTML] Roles of PI3K/AKT/GSK3 pathway involved in psychiatric illnesses

S Matsuda, Y Ikeda, M Murakami, Y Nakagawa, A Tsuji… - Diseases, 2019‏ - mdpi.com
Psychiatric illnesses may be qualified to the cellular impairments of the function for survival
or death in neurons, which may consequently appear as abnormalities in the neuroplasticity …

Peripheral whole blood microRNA alterations in major depression and bipolar disorder

E Maffioletti, A Cattaneo, G Rosso, G Maina… - Journal of affective …, 2016‏ - Elsevier
Major depression (MD) and bipolar disorder (BD) are severe and potentially life-threating
mood disorders whose etiology is to date not completely understood. MicroRNAs (miRNAs) …

MicroRNAs and exosomes in depression: potential diagnostic biomarkers

J Tavakolizadeh, K Roshanaei… - Journal of Cellular …, 2018‏ - Wiley Online Library
Depression is known as one of important psychiatric disorders which could be associated
with disability among various populations. Diagnostic and statistical manual of mental …

Molecular biomarkers of depression

A Gururajan, G Clarke, TG Dinan, JF Cryan - … & Biobehavioral Reviews, 2016‏ - Elsevier
Depression is the leading psychiatric disorder worldwide with a significant economic and
emotional strain on society. There is a need for robust biomarkers which will help improve …

The role of microRNAs in depression

R Ding, D Su, Q Zhao, Y Wang, JY Wang… - Frontiers in …, 2023‏ - frontiersin.org
Major depressive disorder (MDD) is a psychiatric disorder with increasing prevalence
worldwide. It is a leading cause of disability and suicide, severely affecting physical and …

Non-coding RNAs in depression: Promising diagnostic and therapeutic biomarkers

Y Shi, Q Wang, R Song, Y Kong, Z Zhang - EBioMedicine, 2021‏ - thelancet.com
Abstract Non-coding RNAs (ncRNAs), including microRNAs, circular RNAs, and long non-
coding RNAs, are important regulators of normal biological processes and their abnormal …

Major depression and its treatment: microRNAs as peripheral biomarkers of diagnosis and treatment response

JP Lopez, A Kos, G Turecki - Current opinion in psychiatry, 2018‏ - journals.lww.com
In this review, we discuss the growing field, investigating peripheral miRNAs as potential
biomarkers of major depression and treatment response. A noninvasive and validated …

Potential of circulating miRNAs as molecular markers in mood disorders and associated suicidal behavior

B Roy, S Ochi, Y Dwivedi - International journal of molecular sciences, 2023‏ - mdpi.com
Mood disorders are the most prevalent psychiatric disorders associated with significant
disability, morbidity, and mortality. The risk of suicide is associated with severe or mixed …