Carbon monoxide is now well-established as a small-molecule biological effector in the
human body. Metal–carbonyl complexes are a promising way to achieve safe and controlled …

Quantifying the amount and defining the location of metal ions in cells and organisms are
critical steps in understanding metal homeostasis and how dyshomeostasis causes or is a …

Simple Summary Cancer is among the leading causes of death, and cancer therapy suffers
from many drawbacks, the lack of selectivity being most noteworthy. In this review, we …

Background: Cancer chemotherapy is limited by severe side effects due to unspecific
cytotoxic activity of currently used therapeutics. In order to minimize these unwanted effects …

Photolabile metal‐containing cages are metal complexes that undergo a change in
coordination environment upon exposure to light of an appropriate wavelength. The light …

Metal ion signaling in biology has been studied extensively with ortho‐nitrobenzyl
photocages; however, the low quantum yields and other optical properties are not ideal for …

Metal ions have well-established catalytic and structural roles in proteins. Much of the
knowledge acquired about metalloenzymes has been derived using spectroscopic …

By utilizing thioether ligands, CuproCleav-1 stabilizes Cu+ complexes in aqueous solution
and releases the guest metal ion upon photolysis of the nitrobenzyl group. The photocage …

Cu3G is a Cu (II) complex of a photoactive tetradentate ligand that is cleaved upon UV
irradiation to release Cu. Here we show that the cytotoxicity of Cu3G increases in response …

The photochemical redox reactions of Cu (II)/alanine complexes have been studied in
deaerated solutions over an extensive range of pH, Cu (II) concentration, and alanine …