The interaction between autophagy, Helicobacter pylori, and gut microbiota in gastric carcinogenesis

A Nabavi-Rad, A Yadegar, A Sadeghi, HA Aghdaei… - Trends in …, 2023 - cell.com
Chronic infection with Helicobacter pylori is the primary risk factor for the development of
gastric cancer. Hindering our ability to comprehend the precise role of autophagy during H …

Crosstalk between autophagy and microbiota in cancer progression

Y Wang, J Du, X Wu, A Abdelrehem, Y Ren, C Liu… - Molecular Cancer, 2021 - Springer
Autophagy is a highly conserved catabolic process seen in eukaryotes and is essentially a
lysosome-dependent protein degradation pathway. The dysregulation of autophagy is often …

[HTML][HTML] An antibiotic-free platform for eliminating persistent Helicobacter pylori infection without disrupting gut microbiota

Y Lai, T Zhang, X Yin, C Zhu, Y Du, Z Li… - Acta Pharmaceutica Sinica …, 2024 - Elsevier
Helicobacter pylori (H. pylori) infection remains the leading cause of gastric
adenocarcinoma, and its eradication primarily relies on the prolonged and intensive use of …

Lnc-PLCB1 is stabilized by METTL14 induced m6A modification and inhibits Helicobacter pylori mediated gastric cancer by destabilizing DDX21

M Chang, X Cui, Q Sun, Y Wang, J Liu, Z Sun, J Ren… - Cancer letters, 2024 - Elsevier
Helicobacter pylori (H. pylori) infection is considered to be an important factor in gastric
cancer (GC). Long noncoding RNA (lncRNA) and m6A modification are involved in the …

Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma

Q Xu, H Zhang, H Liu, Y Han, W Qiu, Z Li - Biomaterials, 2022 - Elsevier
Radio-resistance of glioblastoma (GBM) remains a leading cause of radiotherapy failure
because of the protective autophagy induced by X-Ray irradiation and tumor cells' strong …

YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis

N Li, X Xu, Y Zhan, X Fei, Y Ouyang, P Zheng… - Gut …, 2023 - Taylor & Francis
ABSTRACT H. pylori infection is the strongest known risk factor for gastric carcinoma. The
activation of the yes-associated protein 1 (YAP) and β-catenin pathways has been …

Biomaterials for Helicobacter pylori therapy: therapeutic potential and future perspectives

Y Lai, W Wei, Y Du, J Gao, Z Li - Gut Microbes, 2022 - Taylor & Francis
Helicobacter pylori (H. pylori) is the main cause of gastric adenocarcinoma. However, the
traditional antibiotic treatment of H. pylori is limited due to increased antibiotic resistance …

Harness the functions of gut microbiome in tumorigenesis for cancer treatment

MH Lee - Cancer Communications, 2021 - Wiley Online Library
It has been shown that gut microbiota dysbiosis leads to physiological changes and links to
a number of diseases, including cancers. Thus, many cancer categories and treatment …

Metal-Based Nanoparticles: A Prospective Strategy for Helicobacter pylori Treatment

X Yin, Y Lai, Y Du, T Zhang, J Gao… - International Journal of …, 2023 - Taylor & Francis
Helicobacter pylori (H. pylori) is an infectious pathogen and the leading cause of
gastrointestinal diseases, including gastric adenocarcinoma. Currently, bismuth quadruple …

Targeted Sonodynamic Therapy Platform for Holistic Integrative Helicobacter pylori Therapy

X Yin, Y Lai, X Zhang, T Zhang, J Tian, Y Du… - Advanced …, 2025 - Wiley Online Library
Helicobacter pylori (H. pylori) is a primary pathogen associated with gastrointestinal
diseases, including gastric cancer. The increase in resistance to antibiotics, along with the …