Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments
Traditional cancer treatments use nonspecific drugs and monoclonal antibodies to target
tumor cells. Chimeric antigen receptor (CAR)-T cell therapy, however, leverages the immune …
tumor cells. Chimeric antigen receptor (CAR)-T cell therapy, however, leverages the immune …
Optimizing CAR-T cell therapy for solid tumors: current challenges and potential strategies
K Ai, B Liu, X Chen, C Huang, li** Yang… - Journal of Hematology & …, 2024 - Springer
Chimeric antigen receptor (CAR)-T cell therapy demonstrates substantial efficacy in various
hematological malignancies. However, its application in solid tumors is still limited. Clinical …
hematological malignancies. However, its application in solid tumors is still limited. Clinical …
Efficient leukocytes detection and classification in microscopic blood images using convolutional neural network coupled with a dual attention network
Abstract Leukocytes, also called White Blood Cells (WBCs) or leucocytes, are the cells that
play a pivotal role in human health and are vital indicators of diseases such as malaria …
play a pivotal role in human health and are vital indicators of diseases such as malaria …
Detection of frog virus 3 by integrating RPA-CRISPR/Cas12a-SPM with deep learning
A fast, easy-to-implement, highly sensitive, and point-of-care (POC) detection system for frog
virus 3 (FV3) is proposed. Combining recombinase polymerase amplification (RPA) and …
virus 3 (FV3) is proposed. Combining recombinase polymerase amplification (RPA) and …
Leukemia Net: Integrating attention depth wise Separable network-aided stacked feature pooling with weighted recurrent neural network-based leukemia detection …
Leukemia is regarded as one of the fatal disorders that develop in the bone marrow due to
uncontrolled changes in the White Blood Cells (WBC). Leukemia usually causes abnormal …
uncontrolled changes in the White Blood Cells (WBC). Leukemia usually causes abnormal …
Improving chimeric antigen receptor T-cell therapies by using artificial intelligence and internet of things technologies: A narrative review
A Boretti - European Journal of Pharmacology, 2024 - Elsevier
Cancer poses a formidable challenge in the field of medical science, prompting the
exploration of innovative and efficient treatment strategies. One revolutionary breakthrough …
exploration of innovative and efficient treatment strategies. One revolutionary breakthrough …
CRISPR Diagnostics for WHO High-Priority Sexually Transmitted Infections
Sexually transmitted infections (STIs) pose a global health threat. Most of these infections
are curable if detected in a timely and accurate manner. In 2022, the World Health …
are curable if detected in a timely and accurate manner. In 2022, the World Health …
CAR-NKT Cells in Asthma: Use of NKT as a Promising Cell for CAR Therapy
NKT cells, unique lymphocytes bridging innate and adaptive immunity, offer significant
potential for managing inflammatory disorders like asthma. Activating iNKT induces …
potential for managing inflammatory disorders like asthma. Activating iNKT induces …
Advances in manufacturing chimeric antigen receptor immune cell therapies
A Ramamurthy, A Tommasi, K Saha - Seminars in Immunopathology, 2024 - Springer
Biomedical research has witnessed significant strides in manufacturing chimeric antigen
receptor T cell (CAR-T) therapies, marking a transformative era in cellular immunotherapy …
receptor T cell (CAR-T) therapies, marking a transformative era in cellular immunotherapy …
Prompt-enhanced hierarchical transformer elevating cardiopulmonary resuscitation instruction via temporal action segmentation
The vast majority of people who suffer unexpected cardiac arrest are performed
cardiopulmonary resuscitation (CPR) by passersby in a desperate attempt to restore life, but …
cardiopulmonary resuscitation (CPR) by passersby in a desperate attempt to restore life, but …