Juvenile idiopathic arthritis

A Martini, DJ Lovell, S Albani, HI Brunner… - Nature reviews disease …, 2022‏ - nature.com
Juvenile idiopathic arthritis (JIA) is an umbrella term for arthritis of unknown origin, lasting
for> 6 weeks with onset before 16 years of age. JIA is the most common chronic …

Biological classification of childhood arthritis: roadmap to a molecular nomenclature

PA Nigrovic, RA Colbert, VM Holers, S Ozen… - Nature reviews …, 2021‏ - nature.com
Chronic inflammatory arthritis in childhood is heterogeneous in presentation and course.
Most forms exhibit clinical and genetic similarity to arthritis of adult onset, although at least …

Tofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial

N Ruperto, HI Brunner, O Synoverska, TV Ting… - The Lancet, 2021‏ - thelancet.com
Background Tofacitinib is an oral Janus kinase inhibitor. This trial assessed the efficacy and
safety of tofacitinib versus placebo in patients with polyarticular course juvenile idiopathic …

Juvenile idiopathic arthritis-associated uveitis

ES Sen, AV Ramanan - Clinical Immunology, 2020‏ - Elsevier
Juvenile idiopathic arthritis (JIA) is the commonest rheumatic disease in children and JIA-
associated uveitis its most frequent extra-articular manifestation. The uveitis is potentially …

Epidemiology and demographics of juvenile idiopathic arthritis in Africa and Middle East

SM Al-Mayouf, M Al Mutairi, K Bouayed… - Pediatric …, 2021‏ - Springer
Abstract Juvenile Idiopathic Arthritis (JIA) is a group of chronic heterogenous disorders that
manifests as joint inflammation in patients aged< 16 years. Globally, approximately 3 million …

Definition and validation of the American College of Rheumatology 2021 juvenile arthritis disease activity score cutoffs for disease activity states in juvenile idiopathic …

C Trincianti, EHP Van Dijkhuizen… - Arthritis & …, 2021‏ - Wiley Online Library
Objective To develop and validate new Juvenile Arthritis Disease Activity Score 10
(JADAS10) and clinical JADAS10 (cJADAS10) cutoffs to separate the states of inactive …

Incidence and prevalence of juvenile idiopathic arthritis in the United Kingdom, 2000–2018: results from the Clinical Practice Research Datalink

R Costello, J McDonagh, KL Hyrich… - Rheumatology, 2022‏ - academic.oup.com
Objective The incidence and prevalence of JIA was last estimated in the UK in 1994. Since
then the disease has been reclassified, the specialty of paediatric rheumatology has evolved …

Context and priorities for health systems strengthening for pain and disability in low-and middle-income countries: a secondary qualitative study and content analysis …

AM Briggs, JE Jordan, S Sharma… - Health policy and …, 2023‏ - academic.oup.com
Musculoskeletal (MSK) health impairments contribute substantially to the pain and disability
burden in low-and middle-income countries (LMICs), yet health systems strengthening …

Global prevalence estimates of three chronic musculoskeletal conditions: club foot, juvenile idiopathic arthritis and juvenile systemic lupus erythematosus

M Dave, J Rankin, M Pearce, HE Foster - Pediatric Rheumatology, 2020‏ - Springer
Background Musculoskeletal (MSK) conditions are a major source of morbidity and
disability. There is a lack of global comparable data on the burden of MSK conditions in …

Treatment of systemic juvenile idiopathic arthritis

CH Hinze, D Foell, C Kessel - Nature Reviews Rheumatology, 2023‏ - nature.com
Systemic juvenile idiopathic arthritis (sJIA) is an inflammatory disease with hallmarks of
severe systemic inflammation, which can be accompanied by arthritis. Contemporary …