[HTML][HTML] Synthetic polycistronic sequences in eukaryotes
X Wang, MA Marchisio - Synthetic and systems biotechnology, 2021 - Elsevier
The need for co-ordinate, high-level, and stable expression of multiple genes is essential for
the engineering of biosynthetic circuits and metabolic pathways. This work outlines the …
the engineering of biosynthetic circuits and metabolic pathways. This work outlines the …
Delivery and use of the CRISPR-Cas systems, vectors and compositions for hepatic targeting and therapy
F Zhang, L Cong, RAN Fei - US Patent 10,577,630, 2020 - Google Patents
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Induced pluripotent stem cell generation using a single lentiviral stem cell cassette
Induced pluripotent stem (iPS) cells can be generated using retroviral vectors expressing
Oct4, Klf4, Sox2, and cMyc. Most prior studies have required multiple retroviral vectors for …
Oct4, Klf4, Sox2, and cMyc. Most prior studies have required multiple retroviral vectors for …
[PDF][PDF] Use of HIV as a gene transfer vector
Despite the extensive research efforts over the past 25 years that have focused on HIV, there
is still no cure for AIDS. However, tremendous progress in the understanding of the structure …
is still no cure for AIDS. However, tremendous progress in the understanding of the structure …
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
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Functional genomics using CRISPR-Cas systems, compositions, methods, screens and applications thereof
2016-06-20 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for targeting disorders and diseases using viral components
F Zhang, L Cong, RAN Fei, M Heidenreich… - US Patent …, 2021 - Google Patents
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Methods, models, systems, and apparatus for identifying target sequences for Cas enzymes or CRISPR-Cas systems for target sequences and conveying results …
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Modeling initiation of Ewing sarcoma in human neural crest cells
C von Levetzow, X Jiang, Y Gwye, G von Levetzow… - PloS one, 2011 - journals.plos.org
Ewing sarcoma family tumors (ESFT) are aggressive bone and soft tissue tumors that
express EWS-ETS fusion genes as driver mutations. Although the histogenesis of ESFT is …
express EWS-ETS fusion genes as driver mutations. Although the histogenesis of ESFT is …
Optimized CRISPR-Cas double nickase systems, methods and compositions for sequence manipulation
F Zhang, P Hsu, C Lin, RAN Fei - US Patent 10,711,285, 2020 - Google Patents
2016-06-14 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …