Abstract 'Jack of all trades, master of everything'is a fair label for transforming growth factor
β1 (TGF-β)–a cytokine that controls our life at many levels. In the adult organism, TGF-β1 is …

Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial lung
disease, characterised by progressive scarring of the lung and associated with a high …

Idiopathic pulmonary fibrosis (IPF) is a fatal age-associated disease that is characterized by
progressive and irreversible scarring of the lung. The pathogenesis of IPF is not completely …

Fibrosis is a pathological feature of most chronic inflammatory diseases. Fibrosis, or
scarring, is defined by the accumulation of excess extracellular matrix components. If highly …

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with poor prognosis and
limited therapeutic options. The incidence of IPF increases with age, and ageing-related …

The fibrotic encapsulation of implants involves the mechanical activation of myofibroblasts
and of pro-fibrotic transforming growth factor beta 1 (TGF-β1). Here, we show that both …

Fibroblasts, which are traditionally recognized as a quiescent cell responsible for
extracellular matrix production, are more and more appreciated as an active key player of …

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive and devastating interstitial
lung disease of unknown etiology, where the normal lung architecture is lost and replaced …

A growing body of evidence indicates that aberrant activation of alveolar epithelial cells and
fibroblasts in an aging lung plays a critical role in the pathogenesis of idiopathic pulmonary …