Analytical methods for obtaining binding parameters of drug–protein interactions: A review

L Wang, W Zhang, Y Shao, D Zhang, G Guo… - Analytica Chimica Acta, 2022 - Elsevier
The study of drug–protein interactions can reveal the corresponding binding mechanisms,
providing valuable information for the early phase drug development and development of …

[HTML][HTML] Derivatives of Pyrimidine Nucleosides Affect Artificial Membranes Enriched with Mycobacterial Lipids

OS Ostroumova, SS Efimova, PD Zlodeeva… - Pharmaceutics, 2024 - mdpi.com
The mechanisms of action of pyrimidine nucleoside derivatives on model lipid membranes
of various compositions were studied. A systematic analysis of the tested agents' effects on …

Langmuir monolayers provide an effective strategy for studying molecular recognition of nucleobases using alkylated nucleotides

FA Moreira, JFB Escobar, C Giordani… - Colloids and Surfaces B …, 2024 - Elsevier
Molecular Recognition in nucleotides is crucial for medicine, underpinning precise
interactions in genetic replication and therapy. Alkylated nucleotides, in particular, play a key …

Continuous flow biocatalysis: synthesis of purine nucleoside esters catalyzed by lipase TL IM from Thermomyces lanuginosus

SY Zhang, GN Fu, LH Du, H Lin, AY Zhang, HJ **e… - RSC …, 2024 - pubs.rsc.org
Purine nucleoside ester is one of the derivatives of purine nucleoside, which has antiviral
and anticancer activities. In this work, a continuous flow synthesis of purine nucleoside …

Prediction of the binding interactions between rosmarinic acid and cysteinyl leukotriene receptor type 1 by molecular docking and immobilized receptor …

B Shi, J Wang - RSC advances, 2024 - pubs.rsc.org
Drug–protein interaction analysis is still at the center of research efforts to illustrate binding
mechanisms and provide valuable information for selecting drug candidates with ideal …

Exploring the physicochemical properties of the integration of Tristearoyl uridine in Langmuir monolayers: An approach to cell membrane modeling for prodrugs

FA Moreira, JFB Escobar, C Giordani, L Caseli - Biophysical Chemistry, 2024 - Elsevier
Understanding the mechanisms by which drugs interact with cell membranes is crucial for
unraveling the underlying biochemical and biophysical processes that occur on the surface …