[HTML][HTML] Functional aspects of plant secondary metabolites in metal stress tolerance and their importance in pharmacology

KS Anjitha, PP Sameena, JT Puthur - Plant Stress, 2021 - Elsevier
Toxic trace metals are ecotoxic due to their high bioaccumulation and toxicity, acting as
abiotic stress agents, causing oxidative damage to the plant cells. Plants can recognize …

Progress and impact of Latin American natural product databases

A Gómez-García, JL Medina-Franco - Biomolecules, 2022 - mdpi.com
Natural products (NPs) are a rich source of structurally novel molecules, and the chemical
space they encompass is far from being fully explored. Over history, NPs have represented a …

A Comprehensive In Silico Exploration of Pharmacological Properties, Bioactivities, Molecular Docking, and Anticancer Potential of Vieloplain F from Xylopia vielana …

SS Hassan, SQ Abbas, F Ali, M Ishaq, I Bano… - Molecules, 2022 - mdpi.com
Compounds derived from plants have several anticancer properties. In the current study,
one guaiane-type sesquiterpene dimer, vieloplain F, isolated from Xylopia vielana species …

Stress driven discovery of natural products from actinobacteria with anti-oxidant and cytotoxic activities including docking and admet properties

SS Hassan, I Muhammad, SQ Abbas… - International Journal of …, 2021 - mdpi.com
Elicitation through abiotic stress, including chemical elicitors like heavy metals, is a new
technique for drug discovery. In this research, the effect of heavy metals on actinobacteria …

Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic …

F Mahmood, JA Khan, MH Mahnashi, MS Jan… - Molecules, 2022 - mdpi.com
In the current study, a series of new (2 S, 3 S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …

Navigating the chemical space and chemical multiverse of a unified Latin American natural product database: LANaPDB

A Gómez-García, DAA Jiménez, WJ Zamora… - Pharmaceuticals, 2023 - mdpi.com
The number of databases of natural products (NPs) has increased substantially. Latin
America is extraordinarily rich in biodiversity, enabling the identification of novel NPs, which …

Assessment of the potential of Dunaliella microalgae for different biotechnological applications: A systematic review

MROB da Silva, YAS Moura, A Converti, ALF Porto… - Algal Research, 2021 - Elsevier
Dunaliella sp. microalgae are well known for their use in the recovery of high value
compounds or as whole cells in various biotechnological applications. The aim of this work …

In-silico anti-inflammatory potential of guaiane dimers from Xylopia vielana targeting COX-2

SS Hassan, WD Zhang, H **, SH Basha… - Journal of …, 2022 - Taylor & Francis
Natural products of herbal origin are prodigious to display diverse pharmacological
activities. In the present study, five guaiane-type sesquiterpene dimers, xylopidimers A− E (1 …

Bridging free radical chemistry with drug discovery: A promising way for finding novel drugs efficiently

ZQ Liu - European Journal of Medicinal Chemistry, 2020 - Elsevier
Many diseases have been regarded to correlate with the in vivo oxidative damages, which
are caused by overproduced free radicals from metabolic process or reactive oxygen …

Chemically Diverse and Biologically Active Secondary Metabolites from Marine Phylum chlorophyta

SAA Shah, SSU Hassan, S Bungau, Y Si, H Xu… - Marine drugs, 2020 - mdpi.com
For a long time, algal chemistry from terrestrial to marine or freshwater bodies, especially
chlorophytes, has fascinated numerous investigators to develop new drugs in the …