Iron oxide nanoparticle-induced autophagic flux is regulated by interplay between p53-mTOR axis and Bcl-2 signaling in hepatic cells

M Uzhytchak, B Smolková, M Lunova, M Jirsa, A Frtús… - Cells, 2020 - mdpi.com
Iron oxide-based nanoparticles have been repeatedly shown to affect lysosomal-mediated
signaling. Recently, nanoparticles have demonstrated an ability to modulate autophagic flux …

Investigating the function of NR4A3 in melanocyte DNA repair and cyto-protection

AC De Almeida Pavarino - 2024 - eprints.qut.edu.au
Melanoma is the deadliest form of skin cancer and Australia has the highest global
incidence of this disease due to a combination of population genetics and environmental UV …

Inhibition of ER stress-associated stress granule formation is a novel vulnerability of mutant p53-expressing cancers

E Thoenen - 2023 - search.proquest.com
Abstract Tumor suppressor p53 (p53) is the most frequently mutated gene in human tumors,
the majority of which are missense mutations. Missense mutant p53 (mutp53) not only loses …

Structure and Function of the Nuclear Pore Complex Revealed by High-Resolution Fluorescence Microscopy

J Kelich, J Yu, W Yang - Nuclear-Cytoplasmic Transport, 2018 - Springer
Nuclear pore complexes (NPCs) are large macromolecular gateways that serve to regulate
the transport of various molecules to and from the nucleus of eukaryotic cells. NPCs mediate …