Immunogenic cell stress and death

G Kroemer, C Galassi, L Zitvogel, L Galluzzi - Nature immunology, 2022 - nature.com
Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Activatable nano-photosensitizers for precise photodynamic cancer therapy

Z Li, Z Zhou, Y Wang, J Wang, L Zhou… - Coordination Chemistry …, 2023 - Elsevier
Owing to the excellent cell ablation ability and low side effects, photodynamic therapy (PDT)
plays an important role in disease treatment, especially cancer. However, most PDT agents …

Boosting checkpoint immunotherapy with biomaterials

L Liu, Y Pan, C Zhao, P Huang, X Chen, L Rao - ACS nano, 2023 - ACS Publications
The immune checkpoint blockade (ICB) therapy has revolutionized the field of cancer
treatment, while low response rates and systemic toxicity limit its clinical outcomes. With the …

Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery

MK Shim, S Yang, IC Sun, K Kim - Advanced Drug Delivery Reviews, 2022 - Elsevier
As immunogenic cell death (ICD) inducers initiating antitumor immune responses, certain
chemotherapeutic drugs have shown considerable potential to reverse the …

A Microenvironment Dual‐Responsive Nano‐Drug Equipped with PD‐L1 Blocking Peptide Triggers Immunogenic Pyroptosis for Prostate Cancer Self‐Synergistic …

H Wang, Z Gao, D Jiao, Y Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Induction of immunogenic cell death (ICD) in tumor combined with immune checkpoint
blockade (ICB) therapy is widely developed to improve the efficacy of cancer …

Carrier-free nanomedicines for cancer treatment

LH Liu, XZ Zhang - Progress in Materials Science, 2022 - Elsevier
The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Nanotherapeutic intervention in photodynamic therapy for cancer

AM Itoo, M Paul, SG Padaga, B Ghosh, S Biswas - ACS omega, 2022 - ACS Publications
The clinical need for photodynamic therapy (PDT) has been growing for several decades.
Notably, PDT is often used in oncology to treat a variety of tumors since it is a low-risk …

[HTML][HTML] Anti-PD-L1 peptide-conjugated prodrug nanoparticles for targeted cancer immunotherapy combining PD-L1 blockade with immunogenic cell death

Y Moon, MK Shim, J Choi, S Yang, J Kim, WS Yun… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Cancer immunotherapy combining immune checkpoint blockade (ICB) with
chemotherapeutic drugs has provided significant clinical advances. However, such …