The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Traumatic brain injury (TBI) represents a significant cause of death and disability in
industrialized countries. Of particular importance to patients the chronic effect that TBI has on …

Oxidative damage plays a critical role in many diseases of the central nervous system. This
study was conducted to determine the molecular mechanisms involved in the putative anti …

The NF-E2-related factor 2 (Nrf2)/antioxidant response element (ARE) pathway plays a
critical role in protecting against oxidative stress in brain ischemia and reperfusion injury …

Relevance-based selectivity and high energy cost are two distinct features of long-term
memory (LTM) formation that warrant its default inhibition. Spaced repetition of learning is a …

J. Neurochem.(2010) 112, 1500–1512. Abstract Recently more evidences support baicalein
(Bai) is neuroprotective in models of ischemic stroke. This study was conducted to determine …

Dopamine D1-like receptors consisting of D1 and D5 subtypes are intimately implicated in
dopaminergic regulation of fundamental neurophysiologic processes such as mood …

Astrocytes are vital structures that support and/or protect neighboring neurons from
pathology. Although it is generally accepted that glutamate receptors mediate most astrocyte …

Recent studies have shown that sigma‐1 receptor orthodox agonists can inhibit
neuroinflammation. SKF 83959 (3‐methyl‐6‐chloro‐7, 8‐hydroxy‐1‐[3‐methylphenyl]‐2, 3 …

In addition to its role as a neurotransmitter, dopamine can stimulate neurite outgrowth and
morphological effects upon primary neurons. To investigate the signal transduction …