Chromatin variants reveal the genetic determinants of oncogenesis in breast cancer

S Bahl, JS Carroll, M Lupien - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Breast cancer presents as multiple distinct disease entities. Each tumor harbors diverse cell
populations defining a phenotypic heterogeneity that im**es on our ability to treat patients …

NOP16 is a histone mimetic that regulates Histone H3K27 methylation and gene repression

K Takashima, DJ Lee, MF Trovero, MH Rothi, M Mistry… - bioRxiv, 2023 - biorxiv.org
Post-translational modifications of histone tails alter chromatin accessibility to regulate gene
expression. Some viruses exploit the importance of histone modifications by expressing …

Epigenomic tumor evolution under the spotlight: the promises of single-cell approaches

C Vallot - Comptes Rendus. Biologies, 2022 - comptes-rendus.academie-sciences …
Cancer evolution was long-reduced to a genetic equation. The latest technological and
subsequent conceptual advances, catalyzed by single-cell approaches, now begin to reveal …