Covering: up to 2022 Pentacyclic triterpenoids are important natural bioactive substances
that are widely present in plants and fungi. They have significant medicinal efficacy, play an …

Triterpenoids are among the most assorted class of specialized metabolites found in all the
taxa of living organisms. Triterpenoids are the leading active ingredients sourced from plant …

Horse chestnut (Aesculus chinensis) is an important medicinal tree that contains various
bioactive compounds, such as aescin, barrigenol-type triterpenoid saponins (BAT), and …

Plants are an excellent source of drug leads. However availability is limited by access to
source species, low abundance and recalcitrance to chemical synthesis. Although plant …

Triterpenoids are widespread bioactive plant defence compounds with potential use as
pharmaceuticals, pesticides and other high-value products. Enzymes belonging to the …

Plants respond to stresses by producing a broad spectrum of bioactive specialized
metabolites. Hormonal elicitors, such as jasmonates, trigger a complex signaling circuit …

Cytochrome P450 monooxygenases (P450s) represent the largest enzyme family of the
plant metabolism. Plants typically devote about 1% of the protein-coding genes for the …

Glycosylation is one of the most prevalent molecular modifications in nature. Single or
multiple sugars can decorate a wide range of acceptors from proteins to lipids, cell wall …

Saponins are a structurally diverse family of triterpenes that are widely found as main
constituents in many traditional plant-based medicines and often have bioactivities of …

Celastrol, a quinone‐methide triterpenoid, was extracted from Tripterygium wilfordii Hook. F.
in 1936 for the first time. Almost 70 years later, it is considered one of the molecules most …