Complicity of degradable polymers in health-care applications
Polymeric biomaterials have revolutionized biomedical technology and related fields as
biomaterials for health-care applications. Recent trend in polymeric medical technology has …
biomaterials for health-care applications. Recent trend in polymeric medical technology has …
[HTML][HTML] Review of current and “omics” methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms
ETHNOPHARMACOLOGICAL RELEVANCE: The increasing use of traditional herbal
medicines around the world requires more scientific evidence for their putative …
medicines around the world requires more scientific evidence for their putative …
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing
D Basketter, H Clewell, I Kimber, A Rossi… - 2012 - wellbeingintlstudiesrepository.org
Systemic toxicity testing forms the cornerstone for the safety evaluation of substances.
Pressures to move from traditional animal models to novel technologies arise from various …
Pressures to move from traditional animal models to novel technologies arise from various …
Consensus report on the future of animal-free systemic toxicity testing
M Leist, N Hasiwa, C Rovida, M Daneshian… - 2014 - kops.uni-konstanz.de
Since March 2013, animal use for cosmetics testing for the European market has been
banned. This requires a renewed view on risk assessment in this field. However, in other …
banned. This requires a renewed view on risk assessment in this field. However, in other …
Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytes
Induced pluripotent stem cells (iPSC) and their differentiated derivatives offer a unique
source of human primary cells for toxicity screens. Here, we report on the comparative …
source of human primary cells for toxicity screens. Here, we report on the comparative …
Pluripotent stem cells in developmental toxicity testing: a review of methodological advances
Millions of children are born each year with a birth defect. Many of these defects are caused
by environmental factors, although the underlying etiology is often unknown. In vivo …
by environmental factors, although the underlying etiology is often unknown. In vivo …
Toxicity of nano-and ionic silver to embryonic stem cells: a comparative toxicogenomic study
Background The widespread application of silver nanoparticles (AgNPs) and silver-
containing products has raised public safety concerns about their adverse effects on human …
containing products has raised public safety concerns about their adverse effects on human …
In vitro models of human development and their potential application in developmental toxicity testing
M Niethammer, T Burgdorf, E Wistorf… - …, 2022 - journals.biologists.com
Recent publications describe the development of in vitro models of human development, for
which applications in developmental toxicity testing can be envisaged. To date, these …
which applications in developmental toxicity testing can be envisaged. To date, these …
[HTML][HTML] Pluripotent stem cell assays: Modalities and applications for predictive developmental toxicity
This manuscript provides a review focused on embryonic stem cell-based models and their
place within the landscape of alternative developmental toxicity assays. Against the …
place within the landscape of alternative developmental toxicity assays. Against the …
Polymer biocompatibility
Polymers are very versatile materials and are used in many applications including
pharmaceutical applications. Natural polymers, modified natural polymers, and synthetic …
pharmaceutical applications. Natural polymers, modified natural polymers, and synthetic …