[HTML][HTML] An overview of mild traumatic brain injuries and emerging therapeutic targets

JP Bielanin, SAH Metwally, SS Paruchuri… - Neurochemistry …, 2024 - Elsevier
The majority of traumatic brain injuries (TBIs), approximately 90%, are classified as mild
(mTBIs). Globally, an estimated 4 million injuries occur each year from concussions or …

Biofluid biomarkers in traumatic brain injury: a systematic sco** review

M Edalatfar, SM Piri, MM Mehrabinejad, MS Mousavi… - Neurocritical care, 2021 - Springer
Emerging evidence suggests that biofluid-based biomarkers have diagnostic and prognostic
potential in traumatic brain injuries (TBI). However, owing to the lack of a conceptual …

Platelet-to-lymphocyte ratio predicts short-term mortality in patients with moderate to severe traumatic brain injury

W Li, W Deng - Scientific Reports, 2022 - nature.com
An easily accessible biomarker with good diagnostic power for patients with traumatic brain
injury (TBI) was needed to predict the short-term mortality. Studies have shown that platelet …

Assessment of long-term effects of sports-related concussions: biological mechanisms and exosomal biomarkers

A Ledreux, MK Pryhoda, K Gorgens… - Frontiers in …, 2020 - frontiersin.org
Concussion or mild traumatic brain injury (mTBI) in athletes can cause persistent symptoms,
known as post-concussion syndrome (PCS), and repeated injuries may increase the long …

Biomarkers in traumatic brain injury: new concepts

D Slavoaca, D Muresanu, C Birle, OV Rosu… - Neurological …, 2020 - Springer
Traumatic brain injury is a multifaceted condition that encompasses a spectrum of injuries:
contusions, axonal injuries in specific brain regions, edema, and hemorrhage. Brain injury …

Biofluid, Imaging, Physiological, and Functional Biomarkers of Mild Traumatic Brain Injury and Subconcussive Head Impacts

K Beard, AK Gauff, AM Pennington… - Journal of …, 2024 - liebertpub.com
Post-concussive symptoms are frequently reported by individuals who sustain mild traumatic
brain injuries (mTBIs) and subconcussive head impacts, even when evidence of intracranial …

Post-mortem detection of neuronal and astroglial biochemical markers in serum and urine for diagnostics of traumatic brain injury

M Olczak, ŁA Poniatowski, A Siwińska… - International Journal of …, 2023 - Springer
Currently available epidemiological data shows that traumatic brain injury (TBI) represents
one of the leading causes of death that is associated with medico-legal practice, including …

mTBI biological biomarkers as predictors of Postconcussion Syndrome

E Stępniewska, M Kałas, J Świderska, M Siemiński - Brain sciences, 2024 - mdpi.com
Postconcussion syndrome (PCS) is one of the leading complications that may appear in
patients after mild head trauma. Every day, thousands of people, regardless of age, gender …

[HTML][HTML] Recent trends and innovations in biosensors development for biomarkers towards monitoring traumatic brain injury

MR Borumand, F Babaloii, SA Mirmotahari… - … and bioelectronics: X, 2022 - Elsevier
Traumatic brain injury (TBI) is a serious health concern and a leading cause of death in all
age groups, especially adults. Although the processes of prevention, lifestyle modification …