Super-Resolution Second-Harmonic Generation Imaging with Multifocal Structured Illumination Microscopy

C Zhang, F Lin, Y Zhang, H Yang, D Lin, J He… - Nano Letters, 2023 - ACS Publications
Second-harmonic generation (SHG) is a noninvasive imaging technique that enables the
exploration of physiological structures without the use of an exogenous label. However …

Effect of out of plane orientation on polarization second harmonic generation of single collagen fibrils

MA Harvey, R Cisek, D Tokarz… - Biomedical Optics Express, 2023 - opg.optica.org
Second harmonic generation (SHG) microscopy has emerged as a powerful technique for
visualizing collagen organization within tissues. Amongst the many advantages of SHG is its …

[HTML][HTML] Spheroids as a 3D in vitro model to study bone and bone mineralization

D Boscaro, P Sikorski - Biomaterials Advances, 2024 - Elsevier
Traumas, fractures, and diseases can severely influence bone tissue. Insight into bone
mineralization is essential for the development of therapies and new strategies to enhance …

Characterization of pathological stomach tissue using polarization-sensitive second harmonic generation microscopy

H Jeon, MA Harvey, R Cisek, E Bennett… - Biomedical Optics …, 2023 - opg.optica.org
Alterations in collagen ultrastructure between human gastric adenocarcinoma and normal
gastric tissue were investigated using polarization-resolved second harmonic generation …

Polarimetric second-harmonic generation microscopy of partially oriented fibers I: Digital modeling

M Alizadeh, S Krouglov, V Barzda - Biophysical Journal, 2023 - cell.com
Second-harmonic generation (SHG) in biological tissues originates predominantly from
noncentrosymmetric fibrillar structures partially oriented within a focal volume (voxel) of a …

Impact of Paraben on Uterine Collagen: An Integrated and Targeted Correlative Approach Using Second Harmonic Generation Microscopy, Nanoindentation, and …

MR Arshee, R Shukla, J Li, U Doha, IC Bagchi… - Journal of the …, 2025 - Elsevier
This study investigates the structural and mechanical changes in uterine collagen following
exposure to propylparaben (PP) using a combined methodology of Second Harmonic …

Corner cutting connects chiral colorimetry to net electric flux in lossless all-dielectric metasurfaces

Z Haddadin, AM Nguyen, LV Poulikakos - arxiv preprint arxiv:2411.05984, 2024 - arxiv.org
All-dielectric metasurfaces can produce structural colors, but the most advantageous design
criteria are still being investigated. This work numerically studies how the two-dimensional …

Polarization Second Harmonic Generation Microscopy for Individual Muscle and Collagen Fibril Ultrastructure Determination

R Cisek, MA Harvey, C MacDonald, D Tokarz - 2024 - academic.oup.com
Intrinsic ultrastructural information about living tissues can be obtained using second
harmonic generation microscopy (SHG). SHG can visualize and structurally interrogate …

Determining the helical pitch and relative polarity of collagen using polarization-resolved SHG

MA Harvey, R Cisek, L Kreplak… - … Microscopy in the …, 2024 - spiedigitallibrary.org
Collagen fibrils are nanoscale biological ropes which are the primary load bearing
structures within the human body. Due to the non-centrosymmetric structure and high …

The effect of cyclic buckling on the structure and mechanical properties of ovine tendon

AJ Yazbek MacDonald - 2024 - library2.smu.ca
Tendons, functionally categorized as positional or energy-storing, have differing structures
and mechanical properties but are both susceptible to damage. Tendinopathy is a chronic …