Why is COVID-19 less severe in children? A review of the proposed mechanisms underlying the age-related difference in severity of SARS-CoV-2 infections
In contrast to other respiratory viruses, children have less severe symptoms when infected
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …
with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this …
Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?
V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …
SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
Although animal models have been evaluated for severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection, none have fully recapitulated the lung disease …
coronavirus 2 (SARS-CoV-2) infection, none have fully recapitulated the lung disease …
[HTML][HTML] The S1 protein of SARS-CoV-2 crosses the blood–brain barrier in mice
EM Rhea, AF Logsdon, KM Hansen, LM Williams… - Nature …, 2021 - nature.com
It is unclear whether severe acute respiratory syndrome coronavirus 2, which causes
coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome …
coronavirus disease 2019, can enter the brain. Severe acute respiratory syndrome …
COVID-19, mast cells, cytokine storm, psychological stress, and neuroinflammation
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …
[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China
L Yang, Z Wang - European journal of medicinal chemistry, 2023 - Elsevier
The ongoing COVID-19 pandemic has resulted in millions of deaths globally, highlighting
the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2 …
the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2 …
Development of ACE2 autoantibodies after SARS-CoV-2 infection
JM Arthur, JC Forrest, KW Boehme, JL Kennedy… - PloS one, 2021 - journals.plos.org
Background Activation of the immune system is implicated in the Post-Acute Sequelae after
SARS-CoV-2 infection (PASC) but the mechanisms remain unknown. Angiotensin …
SARS-CoV-2 infection (PASC) but the mechanisms remain unknown. Angiotensin …
Existence of SARS-CoV-2 entry molecules in the oral cavity
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor, angiotensin-
converting enzyme 2 (ACE2), transmembrane protease serine 2 (TMPRSS2), and furin …
converting enzyme 2 (ACE2), transmembrane protease serine 2 (TMPRSS2), and furin …
K18-hACE2 mice develop respiratory disease resembling severe COVID-19
SARS-CoV-2 emerged in late 2019 and resulted in the ongoing COVID-19 pandemic.
Several animal models have been rapidly developed that recapitulate the asymptomatic to …
Several animal models have been rapidly developed that recapitulate the asymptomatic to …