The transition between epithelial and mesenchymal phenotype is emerging as a key
determinant of tumor cell invasion and metastasis. It is a plastic process in which epithelial …

Several lines of evidence indicate that during transformation epithelial cancer cells can
acquire mesenchymal features via a process called epithelial‐to‐mesenchymal transition …

In the mammary gland, the stromal extracellular matrix (ECM) undergoes dramatic changes
during development and in tumorigenesis. For example, normal adult breast tissue is largely …

In recent years, lipid metabolism has gained greater attention in several diseases including
cancer. Dysregulation of fatty acid metabolism is a key component in breast cancer …

Cancer cells undergo transient EMT and MET phenomena or vice versa, along with the
parallel interplay of various markers, often correlated as the determining factor in decoding …

Leptin is a hormone secreted mainly by adipocytes; physiologically, it participates in the
control of appetite and energy expenditure. However, it has also been linked to tumor …

Studies of dietary fat intake and breast cancer have been inconsistent and few have
examined specific fatty acids. We examined the association between specific …

Epidemiological and animal studies suggest an association between dietary fatty acids and
an increase risk of develo** breast cancer. Obesity, which is characterized by …

The epithelial-to-mesenchymal (-like) transition (EMT), a crucial embryonic development
program, has been linked to the regulation of glioblastoma (GBM) progression and invasion …

A high incidence of tumor recurrence and metastasis has been reported in breast cancer
patients; nevertheless, the underlying molecular mechanisms are largely unknown …