miRNAs as potential game-changers in retinoblastoma: Future clinical and medicinal uses

AS Doghish, HAM Moustafa, MS Elballal… - … -Research and Practice, 2023 - Elsevier
Retinoblastoma (RB) is a rare tumor in children, but it is the most common primitive
intraocular malignancy in childhood age, especially those below three years old. The RB …

Innovative nanotechnology in drug delivery systems for advanced treatment of posterior segment ocular diseases

Y Wu, X Li, X Fu, X Huang, S Zhang, N Zhao… - Advanced …, 2024 - Wiley Online Library
Funduscopic diseases, including diabetic retinopathy (DR) and age‐related macular
degeneration (AMD), significantly impact global visual health, leading to impaired vision and …

[HTML][HTML] Multi-functionalized nanomaterials and nanoparticles for diagnosis and treatment of retinoblastoma

R Arshad, M Barani, A Rahdar, S Sargazi… - Biosensors, 2021 - mdpi.com
Retinoblastoma is a rare type of cancer, and its treatment, as well as diagnosis, is
challenging, owing to mutations in the tumor-suppressor genes and lack of targeted …

Paediatric proton therapy

H Thomas, B Timmermann - The British journal of radiology, 2020 - academic.oup.com
Proton beam therapy is a highly conformal form of radiation therapy, which currently
represents an important therapeutic component in multidisciplinary management in …

[HTML][HTML] The therapeutic use of quercetin in ophthalmology: Recent applications

L Zhao, H Wang, X Du - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Quercetin is a natural flavonol antioxidant found in various plant sources and food samples.
It is well known for its notable curative effects on the treatment of ophthalmic diseases due to …

Role of non-coding RNAs and exosomal non-coding RNAs in retinoblastoma progression

N Ahangar Davoodi, S Najafi… - Frontiers in Cell and …, 2022 - frontiersin.org
Retinoblastoma (RB) is a rare aggressive intraocular malignancy of childhood that has the
potential to affect vision, and can even be fatal in some children. While the tumor can be …

Single-cell characterization of malignant phenotypes and microenvironment alteration in retinoblastoma

C Wu, J Yang, W **ao, Z Jiang, S Chen, D Guo… - Cell death & …, 2022 - nature.com
Retinoblastoma (RB) is the most common primary intraocular malignancy of childhood. It is
known that the tumor microenvironment (TME) regulates tumorigenesis and metastasis …

Application of iontophoresis in ophthalmic practice: an innovative strategy to deliver drugs into the eye

D Wei, N Pu, SY Li, YG Wang, Y Tao - Drug delivery, 2023 - Taylor & Francis
Delivery of drugs to special locations of ocular lesions, while minimizing systemic and local
toxic effects, is recognized as a critical challenge in the ophthalmic practice. The special …

Human papillomavirus infection during pregnancy and childhood: a comprehensive review

A Ardekani, E Taherifard, A Mollalo, E Hemadi… - Microorganisms, 2022 - mdpi.com
Human papillomavirus (HPV), the most prevalent sexually transmitted disease worldwide, is
the causative agent for several genital and oropharyngeal cancers and a suspected agent …

Ocular therapies with biomacromolecules: from local injection to eyedrop and emerging noninvasive delivery strategies

X Fan, K Jiang, F Geng, W Lu, G Wei - Advanced Drug Delivery Reviews, 2023 - Elsevier
The last two decades have witnessed a continuously increasing number of
biomacromolecules approved for the treatment of ocular diseases. The eye possesses …