Automated tomographic reconstruction is now possible in the IMOD software package,
including the merging of tomograms taken around two orthogonal axes. Several …

New developments in the field of microscopy enable to acquire increasing amounts of
information from large sample areas and at an increased resolution. Depending on the …

Correlative light and electron microscopy allows features of interest defined by fluorescence
signals to be located in an electron micrograph of the same sample. Rare dynamic events or …

The correlation of different microscopic imaging techniques alongside with microanalytical
methods is crucial to better understand biological processes on a subcellular level. For that …

In cryogenic correlated light and electron microscopy (cryo-CLEM), frozen targets of interest
are identified and located on EM grids by fluorescence microscopy and then imaged at …

Transmission electron microscopy (TEM) is an important tool for studies in cell biology, and
is essential to address research questions from bacteria to animals. Recent technological …

The accurate segregation of chromosomes during female meiosis relies on the precise
assembly and function of the meiotic spindle, a dynamic structure primarily composed of …

In a previous study, the coexistence of different aggregation pathways of insulin and β-
amyloid (Aβ) peptides was demonstrated by correlative stimulated emission depletion …

We have developed methods to compute tomographic reconstructions of relatively large
areas and volumes of sectioned cells using SerialEM and IMOD. The SerialEM program has …

A method is described whereby quantum dot (QD) nanoparticles can be used for correlative
immunocytochemical studies of human pathology tissue using widefield fluorescence light …