Harnessing the potential of hydrogels for advanced therapeutic applications: Current achievements and future directions

P Lu, D Ruan, M Huang, M Tian, K Zhu… - Signal transduction and …, 2024 - nature.com
The applications of hydrogels have expanded significantly due to their versatile, highly
tunable properties and breakthroughs in biomaterial technologies. In this review, we cover …

The structures and biological functions of polysaccharides from traditional Chinese herbs

P Zeng, J Li, Y Chen, L Zhang - Progress in molecular biology and …, 2019 - Elsevier
Most of traditional Chinese medicine substances come from herbal plants. The medicinal
quality of herbal plants varies with the locations of cultivation, the parts of the herb collected …

Glycosaminoglycans and glycosaminoglycan mimetics in cancer and inflammation

S Morla - International journal of molecular sciences, 2019 - mdpi.com
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all
mammalian cells and usually covalently attached to proteins, forming proteoglycans. They …

The challenge and promise of glycomics

RD Cummings, JM Pierce - Chemistry & biology, 2014 - cell.com
Glycomics is a broad and emerging scientific discipline focused on defining the structures
and functional roles of glycans in biological systems. The staggering complexity of the …

Flavivirus entry receptors: an update

M Perera-Lecoin, L Meertens, X Carnec, A Amara - Viruses, 2013 - mdpi.com
Flaviviruses enter host cells by endocytosis initiated when the virus particles interact with
cell surface receptors. The current model suggests that flaviviruses use at least two different …

Chemical synthesis of glycosaminoglycans

M Mende, C Bednarek, M Wawryszyn, P Sauter… - Chemical …, 2016 - ACS Publications
Glycosaminoglycans (GAGs) as one major part of the glycocalyx are involved in many
essential biological cell processes, as well as in many courses of diseases. Because of the …

Cell-surface heparan sulfate proteoglycans as multifunctional integrators of signaling in cancer

N Hassan, B Greve, NA Espinoza-Sánchez, M Götte - Cellular Signalling, 2021 - Elsevier
Proteoglycans (PGs) represent a large proportion of the components that constitute the
extracellular matrix (ECM). They are a diverse group of glycoproteins characterized by a …

TGF-β family co-receptor function and signaling

J Nickel, P Ten Dijke, TD Mueller - Acta biochimica et …, 2018 - academic.oup.com
Transforming growth factor-β (TGF-β) family members, which include TGF-βs, activins and
bone morphogenetic proteins, are pleiotropic cytokines that elicit cell type-specific effects in …

Entry of Listeria monocytogenes in mammalian epithelial cells: an updated view

J Pizarro-Cerdá, A Kühbacher… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Listeria monocytogenes is a bacterial pathogen that promotes its internalization into host
epithelial cells. Interaction between the bacterial surface molecules InlA and InlB and their …

[HTML][HTML] Glycosaminoglycan-based biomaterials for growth factor and cytokine delivery: Making the right choices

D Hachim, TE Whittaker, H Kim, MM Stevens - Journal of Controlled …, 2019 - Elsevier
Controlled, localized drug delivery is a long-standing goal of medical research, realization of
which could reduce the harmful side-effects of drugs and allow more effective treatment of …