Good sleep and mood are important for health and for kee** active. Numerous studies
have suggested that the incidence of insomnia and depressive disorder are linked to …

The mammalian circadian system, which is comprised of multiple cellular clocks located in
the organs and tissues, orchestrates their regulation in a hierarchical manner throughout the …

The pathophysiology of affective disorders—particularly circuit-level mechanisms underlying
bidirectional, periodic affective state transitions—remains poorly understood. In patients …

Life on earth has adapted to the day-night cycle by evolution of internal, so-called circadian
clocks that adjust behavior and physiology to the recurring changes in environmental …

Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …

Is engaging with music good for your mental health? This question has long been the topic
of empirical clinical and nonclinical investigations, with studies indicating positive …

Circadian rhythm disturbances are a common symptom among individuals with mood
disorders. The suprachiasmatic nucleus (SCN), in the ventral part of the anterior …

With aging, significant changes in circadian rhythms occur, including a shift in phase toward
a “morning” chronotype and a loss of rhythmicity in circulating hormones. However, the …

Circadian disruption has become more prevalent in society due to the increase in shift work,
sleep disruption, blue light exposure, and travel via different time zones. The circadian …

The circadian nature of mood and its dysfunction in affective disorders is well recognized,
but the underlying molecular mechanisms are still unclear. Here, we show that the circadian …