Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase

G Yapar, HE Duran, N Lolak, S Akocak, C Türkeş… - Bioorganic …, 2021 - Elsevier
Abstract Aldose reductase (ALR2), one of the metabolically important enzymes, catalyzes
the formation of sorbitol from glucose in the polyol pathway. ALR2 inhibition is required to …

Suppression of 6-hydroxydopamine-induced oxidative stress by hyperoside via activation of Nrf2/HO-1 signaling in dopaminergic neurons

SH Kwon, SR Lee, YJ Park, M Ra, Y Lee… - International journal of …, 2019 - mdpi.com
In our ongoing research to discover natural products with neuroprotective effects,
hyperoside (quercetin 3-O-galactoside) was isolated from Acer tegmentosum, which has …

Coumarins from the peel of citrus grown in Colombia: composition, elicitation and antifungal activity

C Ramírez-Pelayo, J Martínez-Quiñones, J Gil… - Heliyon, 2019 - cell.com
The present work analyses the chromatographic profile of the peels from fruits of different
citrus cultivated in Colombia: sweet orange (Citrus sinensis [L.] Osbeck var. Valencia) …

Phloroglucinol derivatives, coumarins and an alkaloid from the roots of Evodia lepta Merr.

XY Ding, JR Wen, WY Lin, GY Huang, Q Feng, L Duan… - Phytochemistry, 2023 - Elsevier
Two previously undescribed phloroglucinol derivatives [(±) evolephloroglucinols A and B],
five unusual coumarins [evolecoumarins A and B and (±) evolecoumarins C–E], and one …

Chemical Constituents with Proprotein Convertase Subtilisin/Kexin Type 9 mRNA Expression Inhibitory Activity from Dried Immature Morus alba Fruits

P Pel, HS Chae, P Nhoek, YM Kim… - Journal of agricultural …, 2017 - ACS Publications
Phytochemical investigation for a chloroform-soluble extract of dried Morus alba fruits,
selected by proprotein convertase subtilisin-kexin type 9 (PCSK9) mRNA expression …

Bioactive Flavaglines and Other Constituents Isolated from Aglaia perviridis

L Pan, UM Acuña, J Li, N Jena, TN Ninh… - Journal of natural …, 2013 - ACS Publications
Eight new compounds, including two cyclopenta [b] benzopyran derivatives (1, 2), two
cyclopenta [b] benzofuran derivatives (3, 4), three cycloartane triterpenoids (5–7), and an …

Chemical constituents of the root bark of Ulmus davidiana var. japonica and their potential biological activities

HM So, JS Yu, Z Khan, L Subedi, YJ Ko, IK Lee… - Bioorganic …, 2019 - Elsevier
The root bark of Ulmus davidiana var. japonica (Ulmaceae), commonly known as yugeunpi,
has been used as a traditional Korean medicine for the treatment of gastroenteric and …

Discovery of the Potential Biomarkers for Discrimination between Hedyotis diffusa and Hedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis

Y Wang, C Wang, H Lin, Y Liu, Y Li, Y Zhao, P Li, J Liu - Molecules, 2018 - mdpi.com
Hedyotis diffuse Willd.(HD) and Hedyotis corymbosa (L.) Lam.(HC), two closely related
species of the same genus, are both used for health benefits and disease prevention in …

Palladium-catalyzed base-accelerated direct C–H bond alkenylation of phenols to synthesize coumarin derivatives

XS Zhang, ZW Li, ZJ Shi - Organic Chemistry Frontiers, 2014 - pubs.rsc.org
A palladium-catalyzed base-accelerated ortho-selective C–H alkenylation of phenols to
synthesize bioactive coumarin derivatives was developed. The reaction condition was mild …

Characterization of Secondary Metabolites from Purple Ipomoea batatas Leaves and Their Effects on Glucose Uptake

CL Lee, SL Lee, CJ Chen, HC Chen, MC Kao, CH Liu… - Molecules, 2016 - mdpi.com
Ipomoea batatas has long been used in folk medicine for the treatment of hyperglycemia or
as a food additive for the prevention of type 2 diabetes. However, neither the plant extract …