Cytokines, hormones and cellular regulatory mechanisms favoring successful reproduction
MP Piccinni, R Raghupathy, S Saito… - Frontiers in …, 2021 - frontiersin.org
Its semi-allogeneic nature renders the conceptus vulnerable to attack by the maternal
immune system. Several protective mechanisms operate during gestation to correct the …
immune system. Several protective mechanisms operate during gestation to correct the …
The endocrine function of human placenta: an overview
MA Costa - Reproductive biomedicine online, 2016 - Elsevier
During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …
proper fetal development and gestational success. The formation and development of the …
The role of interleukins in recurrent implantation failure: a comprehensive review of the literature
Recurrent implantation failure (RIF) is a multifactorial condition affecting 10–15% of in vitro
fertilization (IVF) couples. Data suggest that functional dysregulation of the endometrial …
fertilization (IVF) couples. Data suggest that functional dysregulation of the endometrial …
The role of progesterone in feto-maternal immunological cross talk
J Szekeres-Bartho - Medical Principles and Practice, 2018 - karger.com
This review aims to provide a brief historical overview of the feto-maternal immunological
relationship, which profoundly influences the outcome of pregnancy. The initial question …
relationship, which profoundly influences the outcome of pregnancy. The initial question …
[HTML][HTML] Decreased PIBF1/IL6/p-STAT3 during the mid-secretory phase inhibits human endometrial stromal cell proliferation and decidualization
M Zhou, H Xu, D Zhang, C Si, X Zhou, H Zhao… - Journal of Advanced …, 2021 - Elsevier
Introduction Recurrent implantation failure (RIF) is a challenging problem of assisted
reproductive technology that arises mainly due to inadequate endometrial receptivity and its …
reproductive technology that arises mainly due to inadequate endometrial receptivity and its …
Dysregulated expression of IDO may cause unexplained recurrent spontaneous abortion through suppression of trophoblast cell proliferation and migration
S Zong, C Li, C Luo, X Zhao, C Liu, K Wang, W Jia… - Scientific reports, 2016 - nature.com
In pregnancy, trophoblast proliferation, migration and invasion are important for the
establishment and maintenance of a successful pregnancy. Impaired trophoblast function …
establishment and maintenance of a successful pregnancy. Impaired trophoblast function …
The role of extracellular vesicles and PIBF in embryo-maternal immune-interactions
Pregnancy represents a unique immunological situation. Though paternal antigens
expressed by the conceptus are recognized by the immune system of the mother, the …
expressed by the conceptus are recognized by the immune system of the mother, the …
Integrating network reconstruction with mechanistic modeling to predict cancer therapies
Signal transduction networks are often rewired in cancer cells. Identifying these alterations
will enable more effective cancer treatment. We developed a computational framework that …
will enable more effective cancer treatment. We developed a computational framework that …
Characterisation of serum progesterone and progesterone-induced blocking factor (PIBF) levels across trimesters in healthy pregnant women
Progesterone-induced blocking factor (PIBF), which plays an important role in maintaining
healthy pregnancies, has shown great promise as a prognostic biomarker for threatened …
healthy pregnancies, has shown great promise as a prognostic biomarker for threatened …
Embryonic extracellular vesicles as informers to the immune cells at the maternal–fetal interface
Extracellular vesicle (EV) exchange is emerging as a novel method of communication at the
maternal–fetal interface. The presence of the EVs has been demonstrated in the …
maternal–fetal interface. The presence of the EVs has been demonstrated in the …