Summary This Year in Review was derived from a personal selection of articles investigating
biological mechanisms of osteoarthritis (OA) and presented at the OARSI World Congress …

Osteoarthritis (OA) is the most prevalent degenerative joint disorder, affecting hundreds of
millions of people globally. Current clinical approaches are confined to providing only …

Osteoarthritis is a common complex disease imposing a large public-health burden. Here,
we performed a genome-wide association study for osteoarthritis, using data across 16.5 …

Background Hip minimum joint space width (mJSW) provides a proxy for cartilage thickness.
This study aimed to conduct a genome-wide association study (GWAS) of mJSW to (i) …

Studies of potential therapeutic targets in osteoarthritis using animal surgical models are
hel** to elucidate osteoarthritis pathology and propel therapeutics development. Further …

The skeletal system is essential for preserving body structure and facilitating mobility;
however, bone diseases frequently result in significant disabilities, necessitating the …

Objective To examine the genetic architecture of cam morphology using alpha angle (AA) as
a proxy measure and conduct an AA genome‐wide association study (GWAS) followed by …

Recent studies using genetically modified mice, pharmacological approaches, and human
samples have highlighted an important role for the epidermal growth factor receptor (EGFR) …

Osteoarthritis (OA) is a degenerative joint disorder and is the leading cause of disability of
people, which negatively impact people's physical and mental health. Although OA causes …

Background Osteoarthritis (OA) is a prevalent musculoskeletal disease resulting in
progressive degeneration of the hyaline articular cartilage within synovial joints. Current …