EBV and Lymphomagenesis
DG Sausen, A Basith, S Muqeemuddin - Cancers, 2023 - mdpi.com
Simple Summary Epstein–Barr virus is a highly prevalent virus associated with a multitude of
diseases, including autoimmune conditions such as multiple sclerosis and many types of …
diseases, including autoimmune conditions such as multiple sclerosis and many types of …
The immunology of DLBCL
T Takahara, S Nakamura, T Tsuzuki, A Satou - Cancers, 2023 - mdpi.com
Simple Summary Diffuse large B-cell lymphoma (DLBCL) is the most common type of
malignant lymphoid neoplasm and includes morphologically and molecularly …
malignant lymphoid neoplasm and includes morphologically and molecularly …
Molecular and clinical diversity in primary central nervous system lymphoma
Background Primary central nervous system lymphoma (PCNSL) is a rare and distinct entity
within diffuse large B-cell lymphoma presenting with variable response rates probably to …
within diffuse large B-cell lymphoma presenting with variable response rates probably to …
Insights into the tumor microenvironment of B cell lymphoma
The standard therapies in lymphoma have predominantly focused on targeting tumor cells
with less of a focus on the tumor microenvironment (TME), which plays a critical role in …
with less of a focus on the tumor microenvironment (TME), which plays a critical role in …
Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNA
JM Heger, J Mattlener, J Schneider, P Gödel, N Sieg… - Blood, 2024 - ashpublications.org
State-of-the-art response assessment of central nervous system lymphoma (CNSL) by
magnetic resonance imaging is challenging and an insufficient predictor of treatment …
magnetic resonance imaging is challenging and an insufficient predictor of treatment …
Diffuse large B-cell lymphoma involving the central nervous system: biologic rationale for targeted therapy
M Roschewski, DJ Hodson - Haematologica, 2023 - pmc.ncbi.nlm.nih.gov
Diffuse large B-cell lymphoma (DLBCL) is an aggressive B-cell lymphoma curable even in
advanced stages. DLBCL involving the central nervous system (CNS) is more difficult to cure …
advanced stages. DLBCL involving the central nervous system (CNS) is more difficult to cure …
Neddylation of protein, a new strategy of protein post-translational modification for targeted treatment of central nervous system diseases
Q Wu, Z Geng, J Lu, S Wang, Z Yu, S Wang… - Frontiers in …, 2024 - frontiersin.org
Neddylation, a type of protein post-translational modification that links the ubiquitin-like
protein NEDD8 to substrate proteins, can be involved in various significant cellular …
protein NEDD8 to substrate proteins, can be involved in various significant cellular …
Transcriptome analysis of diffuse large b-cell lymphoma cells inducibly expressing MyD88 L265P mutation identifies upregulated CD44, LGALS3, NFKBIZ, and BATF …
During innate immune responses, myeloid differentiation primary response 88 (MyD88)
functions as a critical signaling adaptor protein integrating stimuli from toll-like receptors …
functions as a critical signaling adaptor protein integrating stimuli from toll-like receptors …
Single-cell landscape of primary central nervous system diffuse large B-cell lymphoma
N Liu, C Jiang, X Yao, M Fang, X Qiao, L Zhu, Z Yang… - Cell Discovery, 2023 - nature.com
Understanding tumor heterogeneity and immune infiltrates within the tumor-immune
microenvironment (TIME) is essential for the innovation of immunotherapies. Here …
microenvironment (TIME) is essential for the innovation of immunotherapies. Here …
Integrated genetic analyses of immunodeficiency-associated Epstein-Barr virus-(EBV) positive primary CNS lymphomas
Immunodeficiency-associated primary CNS lymphoma (PCNSL) represents a distinct
clinicopathological entity, which is typically Epstein-Barr virus-positive (EBV+) and carries an …
clinicopathological entity, which is typically Epstein-Barr virus-positive (EBV+) and carries an …