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Flavonoid production: current trends in plant metabolic engineering and de novo microbial production
Flavonoids are secondary metabolites that represent a heterogeneous family of plant
polyphenolic compounds. Recent research has determined that the health benefits of fruits …
polyphenolic compounds. Recent research has determined that the health benefits of fruits …
Biological valorization of lignin to flavonoids
Lignin is the most affluent natural aromatic biopolymer on the earth, which is the promising
renewable source for valuable products to promote the sustainability of biorefinery …
renewable source for valuable products to promote the sustainability of biorefinery …
Production of plant natural products through engineered Yarrowia lipolytica
Plant natural products have broad applications in the pharmaceutical, food, cosmetics and
flavor industries. However, the current manufacturing methods for plant natural products …
flavor industries. However, the current manufacturing methods for plant natural products …
Discovery of a unique flavonoid biosynthesis mechanism in fungi by genome mining
Flavonoids are important plant natural products with variable structures and bioactivities. All
known plant flavonoids are generated under the catalysis of a type III polyketide synthase …
known plant flavonoids are generated under the catalysis of a type III polyketide synthase …
Engineering Yarrowia lipolytica as a Chassis for De Novo Synthesis of Five Aromatic-Derived Natural Products and Chemicals
Yarrowia lipolytica is a novel microbial chassis to upgrade renewable low-cost carbon
feedstocks to high-value commodity chemicals and natural products. In this work, we …
feedstocks to high-value commodity chemicals and natural products. In this work, we …
[HTML][HTML] Toward merging bottom–up and top–down model-based designing of synthetic microbial communities
Highlights•Analysis and designing of microbiomes have become a new paradigm in
microbiology.•Understanding and rational engineering of microbiomes require model-based …
microbiology.•Understanding and rational engineering of microbiomes require model-based …
High-crystallinity covalent organic framework synthesized in deep eutectic solvent: potentially effective adsorbents alternative to macroporous resin for flavonoids
M Gao, D Wang, L Deng, S Liu, K Zhang… - Chemistry of …, 2021 - ACS Publications
A critical challenge in the enrichment of active ingredients in natural medicines is the design
of adsorbents with high selectivity and adsorption capacity. Covalent organic frameworks …
of adsorbents with high selectivity and adsorption capacity. Covalent organic frameworks …
Systems Metabolic Engineering of Escherichia coli Coculture for De Novo Production of Genistein
X Liu, L Li, GR Zhao - ACS Synthetic Biology, 2022 - ACS Publications
Genistein is a plant-derived isoflavone possessing various bioactivities to prevent aging,
carcinogenesis, and neurodegenerative and inflammation diseases. As a typical complex …
carcinogenesis, and neurodegenerative and inflammation diseases. As a typical complex …
[HTML][HTML] Metabolic engineering of microbial cell factories for biosynthesis of flavonoids: a review
H Lou, L Hu, H Lu, T Wei, Q Chen - Molecules, 2021 - mdpi.com
Flavonoids belong to a class of plant secondary metabolites that have a polyphenol
structure. Flavonoids show extensive biological activity, such as antioxidative, anti …
structure. Flavonoids show extensive biological activity, such as antioxidative, anti …
Metabolic engineering in Streptomyces albidoflavus for the biosynthesis of the methylated flavonoids sakuranetin, acacetin, and genkwanin
Flavonoids are important plant secondary metabolites showing antioxidant, antitumor, anti-
inflammatory, and antiviral activities, among others. Methylated flavonoids are particularly …
inflammatory, and antiviral activities, among others. Methylated flavonoids are particularly …