The blood–brain barrier (BBB) undergoes functional changes with aging which may
contribute to cognitive decline. A novel, diffusion prepared arterial spin labeling-based MRI …

Cerebrovascular Reactivity (CVR) provides an assessment of the brain's vascular reserve
and has been postulated to be a sensitive marker in cerebrovascular diseases. MRI-based …

BACKGROUND: Increasing evidence suggests that enlarged perivascular spaces (ePVS)
are associated with cognitive dysfunction in aging. However, the pathogenesis of ePVS …

The changes in brain function in response to mild head injury are usually subtle and go
undetected. Physiological biomarkers would aid in the early diagnosis of mild head injury. In …

Background: Spinal cord injuries (SCI) often result in cardiovascular issues, increasing the
risk of stroke and cognitive deficits. Objectives: This study assessed cerebrovascular …

INTRODUCTION Vascular contributions to cognitive impairment and dementia (VCID)
represent a major factor in cognitive decline in older adults. The present study examined the …

BOLD sensitivity to baseline perfusion and blood volume is a well-acknowledged fMRI
confound. Vascular correction techniques based on cerebrovascular reactivity (CVR) might …

Cerebrovascular disease is the second most common cause of cognitive disorders, usually
referred to as vascular contributions to cognitive impairment and dementia (VCID) and …

Small vessel disease (SVD) is a common cause of strokes and dementia. Currently, there
are no treatments; therefore, develo** and validating early biomarkers of disease …

Repetitive mild head injuries incurred while playing organized sports, during car accidents
and falls, or in active military service are a major health problem. These head injuries induce …