Pathogenesis of preterm birth: bidirectional inflammation in mother and fetus

ES Green, PC Arck - Seminars in immunopathology, 2020 - Springer
Abstract Preterm birth (PTB) complicates 5–18% of pregnancies globally and is a leading
cause of maternal and fetal morbidity and mortality. Most PTB is spontaneous and idiopathic …

[HTML][HTML] Brain changes in a maternal immune activation model of neurodevelopmental brain disorders

L Bergdolt, A Dunaevsky - Progress in neurobiology, 2019 - Elsevier
The develo** brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …

Immune cells in term and preterm labor

N Gomez-Lopez, D StLouis, MA Lehr… - Cellular & molecular …, 2014 - nature.com
Labor resembles an inflammatory response that includes secretion of cytokines/chemokines
by resident and infiltrating immune cells into reproductive tissues and the maternal/fetal …

Inflammation and preterm birth

M Cappelletti, S Della Bella, E Ferrazzi… - Journal of Leucocyte …, 2016 - academic.oup.com
Preterm birth is the leading cause of neonatal morbidity and mortality. Although the
underlying causes of pregnancy-associated complication are numerous, it is well …

[PDF][PDF] Maternal inflammation and its ramifications on fetal neurodevelopment

HK Kwon, GB Choi, JR Huh - Trends in immunology, 2022 - cell.com
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …

Understanding the complexity of the immune system during pregnancy

K Racicot, JY Kwon, P Aldo, M Silasi… - American journal of …, 2014 - Wiley Online Library
Progress in our understanding of the role of the maternal immune system during healthy
pregnancy will help us better understand the role of the immune system in adverse …

[HTML][HTML] Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National …

JV Ilekis, E Tsilou, S Fisher, VM Abrahams… - American journal of …, 2016 - Elsevier
Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Immune involvement in schizophrenia and autism: etiology, pathology and animal models

PH Patterson - Behavioural brain research, 2009 - Elsevier
There is increasing evidence of immune involvement in both schizophrenia and autism. Of
particular interest are striking abnormalities in the expression of immune-related molecules …

Intrauterine infection and preterm labor

V Agrawal, E Hirsch - Seminars in Fetal and Neonatal Medicine, 2012 - Elsevier
Preterm labor is defined as labor that begins before 37 completed weeks of pregnancy.
More than 12% of infants born in the USA are preterm. At least 40% of preterm births are …

Interleukin-6 in pregnancy and gestational disorders

JR Prins, N Gomez-Lopez, SA Robertson - Journal of reproductive …, 2012 - Elsevier
IL6 is a multifunctional cytokine with pivotal roles in the inflammatory response and in
directing T cell differentiation in adaptive immunity. IL6 is widely expressed in the female …