Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

Facing and overcoming sensitivity challenges in biomolecular NMR spectroscopy

JH Ardenkjaer‐Larsen, GS Boebinger… - Angewandte Chemie …, 2015 - Wiley Online Library
In the Spring of 2013, NMR spectroscopists convened at the Weizmann Institute in Israel to
brainstorm on approaches to improve the sensitivity of NMR experiments, particularly when …

NMR hyperpolarization techniques for biomedicine

P Nikolaou, BM Goodson… - Chemistry–A European …, 2015 - Wiley Online Library
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo
molecular imaging modalities, ranging from functional imaging of the lungs to metabolic …

[Књига][B] Nuclear spin relaxation in liquids: theory, experiments, and applications

J Kowalewski, L Maler - 2017 - taylorfrancis.com
Nuclear magnetic resonance (NMR) is widely used across many fields of science because
of the rich data it produces, and some of the most valuable data come from studies of …

15N Hyperpolarization by Reversible Exchange Using SABRE-SHEATH

ML Truong, T Theis, AM Coffey… - The journal of …, 2015 - ACS Publications
NMR signal amplification by reversible exchange (SABRE) is a NMR hyperpolarization
technique that enables nuclear spin polarization enhancement of molecules via concurrent …

The 13C hyperpolarized pyruvate generated by ParaHydrogen detects the response of the heart to altered metabolism in real time

E Cavallari, C Carrera, M Sorge, G Bonne, A Muchir… - Scientific reports, 2018 - nature.com
Many imaging methods have been proposed to act as surrogate markers of organ damage,
yet for many candidates the essential biomarkers characteristics of the injured organ have …

Development of new methods in modern selective organic synthesis: preparation of functionalized molecules with atomic precision

VP Ananikov, LL Khemchyan, YV Ivanova… - Russian Chemical …, 2014 - iopscience.iop.org
The challenges of the modern society and the growing demand of high-technology sectors
of industrial production bring about a new phase in the development of organic synthesis. A …

Signal amplification by reversible exchange (SABRE): From discovery to diagnosis

PJ Rayner, SB Duckett - Angewandte Chemie International …, 2018 - Wiley Online Library
Signal amplification by reversible exchange (SABRE) turns typically weak magnetic
resonance responses into strong signals making previously impractical measurements …

Delivering strong 1H nuclear hyperpolarization levels and long magnetic lifetimes through signal amplification by reversible exchange

PJ Rayner, MJ Burns, AM Olaru, P Norcott… - Proceedings of the …, 2017 - pnas.org
Hyperpolarization turns typically weak NMR and MRI responses into strong signals so that
ordinarily impractical measurements become possible. The potential to revolutionize …