Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to
glutamate transporter proteins present in the plasma membranes of both glial cells and …

The basal ganglia comprise several nuclei in the forebrain, diencephalon, and midbrain
thought to play a significant role in the control of posture and movement. It is well recognized …

This paper reviews some of the recent findings on different aspects of the anatomical
organization of the basal ganglia. Attempts have been made to delineate the anatomical …

A novel mechanism for regulating dopamine activity in subcortical sites and its possible
relevance to schizophrenia is proposed. This hypothesis is based on the regulation of …

Early studies by Krebs (1935) suggested that glutamate played a central metabolic role in
brain. The complex compartmentation of glutamate metabolism in brain was first noted by …

Neither normal brain function nor the pathological processes involved in neurological
diseases can be adequately understood without knowledge of the release, uptake and …

This review summarizes the anatomical and functional organization of the frontal cortex of
the rat in comparison to primates. Lesions of the primary motor or of the prefrontal cortex of …

Huntington's disease (HD) is a progressive, fatal neurological condition caused by an
expansion of CAG (glutamine) repeats in the coding region of the Huntington gene. To date …

The description of new dopamine (DA) receptor subtypes, D1-(D1 and D5) and D2-like
(D2A, D2B, D3, D4), has given an impetus to DA research. While selective agonists and …

Evidence derived from many experimental approaches indicates that cholinergic neurons in
the dorsal striatum (caudate-putamen) are responsive to excitatory amino acids …