No marketed inhaled products currently use sustained release formulations such as
liposomes to enhance drug disposition in the lung, but that may soon change. This review …

The design of a drug delivery system and the fabrication of efficient, successful, and targeted
drug carriers are two separate issues that require slightly different design parameters. The …

Controlled Drug Delivery Page 1 Controlled Drug Delivery Page 2 DRUGS AND THE
PHARMACEUTICAL SCIENCES A Series of Textbooks and Monographs Edited by James …

As a prerequisite for the use of liposomes for delivery of biologically active agents,
techniques are required for the efficient and rapid entrapment of such agents in liposomes …

The development of Iiposome-based pharmaceuticals has progressed rapidly from the
laboratory bench to the point of commercialisation, and several products now undergoing …

[57] ABSTRACT A method of expressing a foreign gene in cells of a mam malian organ in
vivo includes the step of injecting genetic material capable of inducing desired gene …

Two rat monoclonal antibodies, 34A and 201B, which specifically bind to a surface
glycoprotein (gp112) of the pulmonary endothelial cell surface, have been coupled to …

The main objective of drug delivery systems is to deliver a drug effectively, specifically to the
site of action and to achieve greater efficacy and minimise the toxic effects compared to …

Abstract A monoclonal antibody (MoAb), 273-34A, specifically binds to an epitope
expressed almost exclusively on capillary endothelial cells of the lung. Within 15 min after iv …

Isoniazid (INH) is one of the primary drugs used in tuberculosis treatment and its
encapsulation in liposomal vesicles can both improve its therapeutic index and minimize …