[HTML][HTML] Obesity and female infertility: potential mediators of obesity's impact

DE Broughton, KH Moley - Fertility and sterility, 2017 - Elsevier
The worldwide upward trend in obesity has been dramatic, now affecting more than 20% of
American women of reproductive age. Obesity is associated with many adverse maternal …

Inflammation and human ovarian follicular dynamics

CE Boots, ES Jungheim - Seminars in reproductive medicine, 2015 - thieme-connect.com
Inflammation is a biologic process that mediates tissue effects including vasodilation,
hyperemia, edema, collagenolysis, and cell proliferation through complex immunologic …

[HTML][HTML] Pregnancy outcomes decline with increasing body mass index: analysis of 239,127 fresh autologous in vitro fertilization cycles from the 2008–2010 Society for …

MP Provost, KS Acharya, CR Acharya, JS Yeh… - Fertility and sterility, 2016 - Elsevier
Objective To examine the effect of body mass index (BMI) on IVF outcomes in fresh
autologous cycles. Design Retrospective cohort study. Setting Not applicable. Patient (s) A …

Single human oocyte transcriptome analysis reveals distinct maturation stage‐dependent pathways impacted by age

S Llonch, M Barragán, P Nieto, A Mallol… - Aging cell, 2021 - Wiley Online Library
Female fertility is inversely correlated with maternal age due to a depletion of the oocyte
pool and a reduction in oocyte developmental competence. Few studies have addressed the …

Human embryos from overweight and obese women display phenotypic and metabolic abnormalities

C Leary, HJ Leese, RG Sturmey - Human reproduction, 2015 - academic.oup.com
STUDY QUESTION Is the developmental timing and metabolic regulation disrupted in
embryos from overweight or obese women? SUMMARY ANSWER Oocytes from overweight …

Effect of weight loss before in vitro fertilization in women with obesity or overweight and infertility: a systematic review and meta-analysis

HG Jeong, S Cho, KJ Ryu, T Kim, H Park - Scientific Reports, 2024 - nature.com
The effect of weight loss before in vitro fertilization (IVF) procedures on pregnancy outcomes
in women with overweight or obesity and infertility remains controversial. In this systematic …

[HTML][HTML] Obesity and reproduction: a committee opinion

Practice Committee of the American Society for … - Fertility and sterility, 2015 - Elsevier
The purpose of this ASRM Practice Committee report is to provide clinicians with principles
and strategies for the evaluation and treatment of couples with infertility associated with …

mTORC1/2 inhibition preserves ovarian function and fertility during genotoxic chemotherapy

KN Goldman, D Chenette, R Arju, FE Duncan… - Proceedings of the …, 2017 - pnas.org
The ovary contains oocytes within immature (primordial) follicles that are fixed in number at
birth. Activation of follicles within this fixed pool causes an irreversible decline in …

[HTML][HTML] The effect of body mass index on the outcomes of first assisted reproductive technology cycles

VA Moragianni, SML Jones, DA Ryley - Fertility and sterility, 2012 - Elsevier
OBJECTIVE: To provide assisted reproductive technology (ART) outcome rates per body
mass index (BMI) category after controlling for potential confounders. DESIGN …

Weighing the impact of obesity on female reproductive function and fertility

ES Jungheim, JL Travieso, MM Hopeman - Nutrition reviews, 2013 - academic.oup.com
Obesity in women is associated with serious reproductive sequelae. Given its prevalence
among women of reproductive age, much recent attention has focused on the mechanisms …