Combined physics-and machine-learning-based method to identify druggable binding sites using SILCS-Hotspots
Identifying druggable binding sites on proteins is an important and challenging problem,
particularly for cryptic, allosteric binding sites that may not be obvious from X-ray, cryo-EM …
particularly for cryptic, allosteric binding sites that may not be obvious from X-ray, cryo-EM …
[HTML][HTML] Exploring the Potential of Biomimetic Peptides in Targeting Fibrillar and Filamentous Alpha-Synuclein—An In Silico and Experimental Approach to …
SA Frantzeskos, MA Biggs, IA Banerjee - Biomimetics, 2024 - mdpi.com
Alpha-synuclein (ASyn) is a protein that is known to play a critical role in Parkinson's
disease (PD) due to its propensity for misfolding and aggregation. Furthermore, this process …
disease (PD) due to its propensity for misfolding and aggregation. Furthermore, this process …
Map** the Distribution and Affinities of Ligand Interaction Sites on Human Serum Albumin
Ligands in many instances interact with a protein at multiple sites with a range of affinities. In
the present study, ligand-protein interaction sites on Human Serum Albumin (HSA) are …
the present study, ligand-protein interaction sites on Human Serum Albumin (HSA) are …