Drosophila: retrotransposons making up telomeres

E Casacuberta - Viruses, 2017 - mdpi.com
Drosophila and extant species are the best-studied telomerase exception. In this organism,
telomere elongation is coupled with targeted retrotransposition of Healing Transposon (HeT …

Telomere dynamic in humans and animals: Review and perspectives in environmental toxicology

M Louzon, M Coeurdassier, F Gimbert, B Pauget… - Environment …, 2019 - Elsevier
Telomeres (TLs) play major roles in stabilizing the genome and are usually shortened with
ageing. The maintenance of TLs is ensured by two mechanisms involving telomerase (TA) …

Studying protein-DNA interactions using atomic force microscopy

EC Beckwitt, M Kong, B Van Houten - Seminars in cell & developmental …, 2018 - Elsevier
Atomic force microscopy (AFM) has made significant contributions to the study of protein-
DNA interactions by making it possible to topographically image biological samples. A …

Silence at the end: how drosophila regulates expression and transposition of telomeric retroelements

S Cacchione, G Cenci, GD Raffa - Journal of Molecular Biology, 2020 - Elsevier
The maintenance of chromosome ends in Drosophila is an exceptional phenomenon
because it relies on the transposition of specialized retrotransposons rather than on the …

Evolving linear chromosomes and telomeres: a C-strand-centric view

NF Lue - Trends in biochemical sciences, 2018 - cell.com
Recent studies have resulted in deeper understanding of a variety of telomere maintenance
mechanisms as well as plausible models of telomere evolution. Often overlooked in the …

Differential mechanisms of tolerance to extreme environmental conditions in tardigrades

D Carrero, JG Pérez-Silva, V Quesada, C López-Otín - Scientific reports, 2019 - nature.com
Tardigrades, also known as water bears, are small aquatic animals that inhabit marine, fresh
water or limno-terrestrial environments. While all tardigrades require surrounding water to …

Fine tuning the level of the Cdc13 telomere-cap** protein for maximal chromosome stability performance

SY Mersaoui, RJ Wellinger - Current Genetics, 2019 - Springer
Chromosome stability relies on an adequate length and complete replication of telomeres,
the physical ends of chromosomes. Telomeres are composed of short direct repeat DNA and …

The Hybrid Incompatibility Genes Lhr and Hmr Are Required for Sister Chromatid Detachment During Anaphase but Not for Centromere Function

JA Blum, S Bonaccorsi, M Marzullo, V Palumbo… - Genetics, 2017 - academic.oup.com
Crosses between Drosophila melanogaster females and Drosophila simulans males
produce hybrid sons that die at the larval stage. This hybrid lethality is suppressed by loss-of …

Nuclear import of Cdc13 limits chromosomal cap**

SY Mersaoui, E Bonnell, RJ Wellinger - Nucleic Acids Research, 2018 - academic.oup.com
Cdc13 is an essential protein involved in telomere maintenance and chromosome cap**.
Individual domain analyses on Cdc13 suggest the presence of four distinct OB-fold domains …

The nanoCUT&RUN technique visualizes telomeric chromatin in Drosophila

T Chen, X Wei, C Courret, M Cui, L Cheng, J Wu… - PLoS …, 2022 - journals.plos.org
Advances in genomic technology led to a more focused pattern for the distribution of
chromosomal proteins and a better understanding of their functions. The recent …