Acceleration of reaction in charged microdroplets
Using high-resolution mass spectrometry, we have studied the synthesis of isoquinoline in a
charged electrospray droplet and the complexation between cytochrome c and maltose in a …
charged electrospray droplet and the complexation between cytochrome c and maltose in a …
ATP-binding cassette transporters in bacteria
▪ Abstract ATP-binding cassette (ABC) transporters couple ATP hydrolysis to the uptake and
efflux of solutes across the cell membrane in bacteria and eukaryotic cells. In bacteria, these …
efflux of solutes across the cell membrane in bacteria and eukaryotic cells. In bacteria, these …
Self-assembly of CdSe− ZnS quantum dot bioconjugates using an engineered recombinant protein
A novel and direct method is described for conjugating protein molecules to luminescent
CdSe− ZnS core− shell nanocrystals (Quantum Dots) for use as bioactive fluorescent probes …
CdSe− ZnS core− shell nanocrystals (Quantum Dots) for use as bioactive fluorescent probes …
The development of a simple empirical scoring function to estimate the binding constant for a protein-ligand complex of known three-dimensional structure
HJ Böhm - Journal of computer-aided molecular design, 1994 - Springer
A new simple empirical function has been developed that estimates the free energy of
binding for a given protein-ligand complex of known 3D structure. The function takes into …
binding for a given protein-ligand complex of known 3D structure. The function takes into …
Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria
Extracellular solute-binding proteins of bacteria serve as chemoreceptors, recognition
constituents of transport systems, and initiators of signal transduction pathways. Over 50 …
constituents of transport systems, and initiators of signal transduction pathways. Over 50 …
Crystal structure of a catalytic intermediate of the maltose transporter
The maltose uptake system of Escherichia coli is a well-characterized member of the ATP-
binding cassette transporter superfamily. Here we present the 2.8-Å crystal structure of the …
binding cassette transporter superfamily. Here we present the 2.8-Å crystal structure of the …
The two-component signaling pathway of bacterial chemotaxis: a molecular view of signal transduction by receptors, kinases, and adaptation enzymes
▪ Abstract The chemosensory pathway of bacterial chemotaxis has become a paradigm for
the two-component superfamily of receptor-regulated phosphorylation pathways. This …
the two-component superfamily of receptor-regulated phosphorylation pathways. This …
Prediction of binding constants of protein ligands: a fast method for the prioritization of hits obtained from de novo design or 3D database search programs
HJ Böhm - Journal of computer-aided molecular design, 1998 - Springer
A dataset of 82 protein–ligand complexes of known 3D structure and binding constant K i
was analysed to elucidate the important factors that determine the strength of protein–ligand …
was analysed to elucidate the important factors that determine the strength of protein–ligand …
CH− π interactions in glycan recognition
Carbohydrate recognition is crucial for biological processes ranging from development to
immune system function to host–pathogen interactions. The proteins that bind glycans are …
immune system function to host–pathogen interactions. The proteins that bind glycans are …
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors
Glutamate is the predominant excitatory neurotransmitter in the mammalian brain. Once
released, its rapid removal from the synaptic cleft is critical for preventing excitotoxicity and …
released, its rapid removal from the synaptic cleft is critical for preventing excitotoxicity and …