Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease

M Perluigi, F Di Domenico… - Physiological …, 2024 - journals.physiology.org
Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders

MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …

Flavonoids: an overview

AN Panche, AD Diwan, SR Chandra - Journal of nutritional science, 2016 - cambridge.org
Flavonoids, a group of natural substances with variable phenolic structures, are found in
fruits, vegetables, grains, bark, roots, stems, flowers, tea and wine. These natural products …

Superoxide ion: generation and chemical implications

M Hayyan, MA Hashim, IM AlNashef - Chemical reviews, 2016 - ACS Publications
Superoxide ion (O2•–) is of great significance as a radical species implicated in diverse
chemical and biological systems. However, the chemistry knowledge of O2•–is rather …

Ultraviolet light induced generation of reactive oxygen species

TL De Jager, AE Cockrell, SS Du Plessis - Ultraviolet light in human health …, 2017 - Springer
As ultraviolet (UV) radiation is naturally and ubiquitously emitted by the sun, almost
everyone is exposed to it on a daily basis, and it is necessary for normal physiological …

Molecular pharmacology of inflammation: Medicinal plants as anti-inflammatory agents

S Tasneem, B Liu, B Li, MI Choudhary… - Pharmacological research, 2019 - Elsevier
Except for an essential step for the pathology of multiple diseases including atherosclerosis
and rheumatoid arthritis, inflammation is an imperative therapeutic target for develo** …

Mitochondria: central organelles for melatonin′ s antioxidant and anti-aging actions

RJ Reiter, DX Tan, S Rosales-Corral, A Galano… - Molecules, 2018 - mdpi.com
Melatonin, along with its metabolites, have long been known to significantly reduce the
oxidative stress burden of aging cells or cells exposed to toxins. Oxidative damage is a …

[HTML][HTML] ROS/oxidative stress signaling in osteoarthritis

P Lepetsos, AG Papavassiliou - … et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
Osteoarthritis is the most common joint disorder with increasing prevalence due to aging of
the population. Its multi-factorial etiology includes oxidative stress and the overproduction of …

Correlation between oxidative stress, nutrition, and cancer initiation

SK Saha, SB Lee, J Won, HY Choi, K Kim… - International journal of …, 2017 - mdpi.com
Inadequate or excessive nutrient consumption leads to oxidative stress, which may disrupt
oxidative homeostasis, activate a cascade of molecular pathways, and alter the metabolic …

Structure-antiradical activity relationships of 25 natural antioxidant phenolic compounds from different classes

A Moazzen, N Öztinen, E Ak-Sakalli, M Koşar - Heliyon, 2022 - cell.com
In this study, 11 hydroxybenzoic acids, 6 hydroxycinnamic acids, 6 flavonoids, and 2
synthetic phenolic antioxidants were evaluated according to their scavenging capacity and …