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[HTML][HTML] Lipid membrane mimetics in functional and structural studies of integral membrane proteins
Background: Open Access Editor's Choice Review Lipid Membrane Mimetics in Functional
and Structural Studies of Integral Membrane Proteins by Saman Majeed 1, Akram Bani …
and Structural Studies of Integral Membrane Proteins by Saman Majeed 1, Akram Bani …
The contribution of modern EPR to structural biology
G Jeschke - Emerging Topics in Life Sciences, 2018 - portlandpress.com
Electron paramagnetic resonance (EPR) spectroscopy combined with site-directed spin
labelling is applicable to biomolecules and their complexes irrespective of system size and …
labelling is applicable to biomolecules and their complexes irrespective of system size and …
Conformations of influenza A M2 protein in DOPC/DOPS and E. coli native lipids and proteins
G Sanders, PP Borbat, ER Georgieva - Biophysical Journal, 2024 - cell.com
We compared the conformations of the transmembrane domain (TMD) of influenza A M2
(IM2) protein reconstituted in 1, 2-dioleoyl-sn-glycero-3-phosphocholine/1, 2-dioleoyl-sn …
(IM2) protein reconstituted in 1, 2-dioleoyl-sn-glycero-3-phosphocholine/1, 2-dioleoyl-sn …
Nanoscale lipid membrane mimetics in spin-labeling and electron paramagnetic resonance spectroscopy studies of protein structure and function
ER Georgieva - Nanotechnology Reviews, 2017 - degruyter.com
Cellular membranes and associated proteins play critical physiological roles in organisms
from all life kingdoms. In many cases, malfunction of biological membranes triggered by …
from all life kingdoms. In many cases, malfunction of biological membranes triggered by …
Paramagnetic species in catalysis research: a unified approach towards (the role of EPR in) heterogeneous, homogeneous and enzyme catalysis
Paramagnetic (open-shell) systems, including transition metal ions, radical intermediates
and defect centres, are often involved in catalytic transformations. Despite the prevalence of …
and defect centres, are often involved in catalytic transformations. Despite the prevalence of …
[HTML][HTML] Molecular biophysics and inhibition mechanism of influenza virus A M2 viroporin by adamantane-based drugs–Challenges in designing antiviral agents
The influenza A matrix 2 (AM2) protein is a prototype viroporin that conducts protons through
an array of water molecules and sidechains of ionizable amino acid residues, with His37 …
an array of water molecules and sidechains of ionizable amino acid residues, with His37 …
[HTML][HTML] Highly versatile small virus-encoded proteins in cellular membranes: A structural perspective on how proteins' inherent conformational plasticity couples with …
We investigated several small viral proteins that reside and function in cellular membranes.
These proteins belong to the viroporin family because they assemble into ion-conducting …
These proteins belong to the viroporin family because they assemble into ion-conducting …
Random mutagenesis analysis of the influenza A M2 proton channel reveals novel resistance mutants
The influenza M2 proton channel is a major drug target, but unfortunately, the acquisition of
resistance mutations greatly reduces the functional life span of a drug in influenza treatment …
resistance mutations greatly reduces the functional life span of a drug in influenza treatment …
Using pulsed EPR in the structural analysis of integral membrane proteins
Pulsed EPR methods, such as PELDOR (or DEER) and ESEEM have emerged as powerful
tools for assessing membrane protein conformation, folding, oligomerisation and dynamics …
tools for assessing membrane protein conformation, folding, oligomerisation and dynamics …
Applications of nitroxide spin labels to structural biology
Nitroxide spin labeling was introduced by McConnell and co-workers in the mid-1960s with
the goals of using electron paramagnetic resonance (EPR) spectroscopy to investigate …
the goals of using electron paramagnetic resonance (EPR) spectroscopy to investigate …