Runs of homozygosity: windows into population history and trait architecture
Long runs of homozygosity (ROH) arise when identical haplotypes are inherited from each
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …
parent and thus a long tract of genotypes is homozygous. Cousin marriage or inbreeding …
Runs of homozygosity: current knowledge and applications in livestock
E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …
BCFtools/RoH: a hidden Markov model approach for detecting autozygosity from next-generation sequencing data
Runs of homozygosity (RoHs) are genomic stretches of a diploid genome that show identical
alleles on both chromosomes. Longer RoHs are unlikely to have arisen by chance but are …
alleles on both chromosomes. Longer RoHs are unlikely to have arisen by chance but are …
Genomic and archaeological evidence suggest a dual origin of domestic dogs
The geographic and temporal origins of dogs remain controversial. We generated genetic
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …
sequences from 59 ancient dogs and a complete (28x) genome of a late Neolithic dog …
How to study runs of homozygosity using PLINK? A guide for analyzing medium density SNP data in livestock and pet species
Background PLINK is probably the most used program for analyzing SNP genotypes and
runs of homozygosity (ROH), both in human and in animal populations. The last decade …
runs of homozygosity (ROH), both in human and in animal populations. The last decade …
A high-coverage genome sequence from an archaic Denisovan individual
We present a DNA library preparation method that has allowed us to reconstruct a high-
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
coverage (30×) genome sequence of a Denisovan, an extinct relative of Neandertals. The …
[HTML][HTML] The locust genome provides insight into swarm formation and long-distance flight
Locusts are one of the world's most destructive agricultural pests and represent a useful
model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta …
model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta …
Analysis of runs of homozygosity and their relationship with inbreeding in five cattle breeds farmed in Italy
Increased inbreeding is an inevitable consequence of selection in livestock populations. The
analysis of high‐density single nucleotide polymorphisms (SNPs) facilitates the identification …
analysis of high‐density single nucleotide polymorphisms (SNPs) facilitates the identification …
Estimating autozygosity from high-throughput information: effects of SNP density and genoty** errors
Background Runs of homozygosity are long, uninterrupted stretches of homozygous
genotypes that enable reliable estimation of levels of inbreeding (ie, autozygosity) based on …
genotypes that enable reliable estimation of levels of inbreeding (ie, autozygosity) based on …
[HTML][HTML] Evaluation of inbreeding depression in Holstein cattle using whole-genome SNP markers and alternative measures of genomic inbreeding
The effects of increased pedigree inbreeding in dairy cattle populations have been well
documented and result in a negative impact on profitability. Recent advances in genoty** …
documented and result in a negative impact on profitability. Recent advances in genoty** …