Axial spondyloarthritis

J Sieper, D Poddubnyy - The Lancet, 2017‏ - thelancet.com
The term axial spondyloarthritis covers both patients with non-radiographic and radiographic
axial spondyloarthritis, which is also termed ankylosing spondylitis. The disease usually …

Spondyloarthritis

M Dougados, D Baeten - The Lancet, 2011‏ - thelancet.com
Spondyloarthritis is a group of several related but phenotypically distinct disorders: psoriatic
arthritis, arthritis related to inflammatory bowel disease, reactive arthritis, a subgroup of …

Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force

JS Smolen, J Braun, M Dougados, P Emery… - Annals of the rheumatic …, 2014‏ - Elsevier
Background Therapeutic targets have been defined for diseases like diabetes, hypertension
or rheumatoid arthritis and adhering to them has improved outcomes. Such targets are just …

Ankylosing spondylitis

J Braun, J Sieper - The Lancet, 2007‏ - thelancet.com
Ankylosing spondylitis is a common inflammatory rheumatic disease that affects the axial
skeleton, causing characteristic inflammatory back pain, which can lead to structural and …

Cytokines as therapeutic targets in rheumatoid arthritis and other inflammatory diseases

S Siebert, A Tsoukas, J Robertson, I McInnes - Pharmacological reviews, 2015‏ - Elsevier
The human immune system involves highly complex and coordinated processes in which
small proteins named cytokines play a key role. Cytokines have been implicated in the …

Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double‐blind, placebo‐controlled trial

D van der Heijde, A Kivitz, MH Schiff… - … : Official Journal of …, 2006‏ - Wiley Online Library
Objective To evaluate the safety and efficacy of adalimumab, a fully human recombinant
IgG1 monoclonal antibody that specifically targets human tumor necrosis factor, in patients …

ASAS/EULAR recommendations for the management of ankylosing spondylitis

J Zochling, D van der Heijde, R Burgos-Vargas… - Annals of the rheumatic …, 2006‏ - Elsevier
Objective: To develop evidence based recommendations for the management of ankylosing
spondylitis (AS) as a combined effort of the 'ASsessment in AS'international working group …

Axial spondyloarthritis

J Sieper, J Braun, M Dougados, D Baeten - Nature reviews Disease …, 2015‏ - nature.com
The term axial spondyloarthritis covers both non-radiographic disease and radiographic
disease (also known as ankylosing spondylitis). Some studies have been performed to …

Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis

X Baraliakos, H Haibel, J Listing, J Sieper… - Annals of the rheumatic …, 2014‏ - Elsevier
Objective Compare the radiographic progression of ankylosing spondylitis (AS) patients
treated with infliximab (INF) versus historical controls (Herne cohort, HC) never treated with …

First update of the international ASAS consensus statement for the use of anti-TNF agents in patients with ankylosing spondylitis

J Braun, J Davis, M Dougados, J Sieper… - Annals of the Rheumatic …, 2006‏ - Elsevier
Objective: To update the international recommendations for use of anti-tumour necrosis
factor (TNF) agents in the treatment of ankylosing spondylitis. Methods: The published …