The peritumoral brain zone in glioblastoma: where we are and where we are going

M Giambra, A Di Cristofori, S Valtorta… - Journal of …, 2023 - Wiley Online Library
Glioblastoma (GBM) is the most aggressive and invasive primary brain tumor. Current
therapies are not curative, and patients' outcomes remain poor with an overall survival of …

Applications of radiomics and radiogenomics in high-grade gliomas in the era of precision medicine

A Fathi Kazerooni, SJ Bagley, H Akbari, S Saxena… - Cancers, 2021 - mdpi.com
Simple Summary Radiomics and radiogenomics offer new insight into high-grade glioma
biology, as well as into glioma behavior in response to standard therapies. In this article, we …

Multi‐ligand functionalized blood‐to‐tumor sequential targeting strategies in the field of glioblastoma nanomedicine

C Martins, B Sarmento - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Glioblastoma (GBM) is an unmet clinical need characterized by a standard of care (SOC) 5‐
year survival rate of only 5%, and a treatment mostly palliative. Significant hurdles in GBM …

Current Status and Future Perspective in Glioma Invasion Research

T Ohnishi - Brain Sciences, 2024 - mdpi.com
Glioblastoma (GBM) is the most malignant brain tumor in adults and shows an extremely
poor prognosis, with a median survival of 15 months [1]. The main reason for this poor …

Amine‐weighted chemical exchange saturation transfer magnetic resonance imaging in brain tumors

NS Cho, A Hagiwara, J Yao, DA Nathanson… - NMR in …, 2023 - Wiley Online Library
Amine‐weighted chemical exchange saturation transfer (CEST) magnetic resonance
imaging (MRI) is particularly valuable as an amine‐and pH‐sensitive imaging technique in …

Peritumoral brain zone in glioblastoma: biological, clinical and mechanical features

A Ballestín, D Armocida, V Ribecco… - Frontiers in …, 2024 - frontiersin.org
Glioblastoma is a highly aggressive and invasive tumor that affects the central nervous
system (CNS). With a five-year survival rate of only 6.9% and a median survival time of eight …

Peptide-Hitchhiking for the Development of Nanosystems in Glioblastoma

F Branco, J Cunha, M Mendes, C Vitorino, JJ Sousa - ACS nano, 2024 - ACS Publications
Glioblastoma (GBM) remains the epitome of aggressiveness and lethality in the spectrum of
brain tumors, primarily due to the blood–brain barrier (BBB) that hinders effective treatment …

Differentiation between glioma recurrence and treatment effects using amide proton transfer imaging: A mini-Bayesian bivariate meta-analysis

K Chen, XW Jiang, L Deng, HL She - Frontiers in Oncology, 2022 - frontiersin.org
Background Amide proton transfer (APT) imaging as an emerging MRI approach has been
used for distinguishing tumor recurrence (TR) and treatment effects (TEs) in glioma patients …

[HTML][HTML] The peritumoral brain zone in glioblastoma: a review of the pretreatment approach

A Michalska-Foryszewska, M Bujko… - Polish Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Glioblastomas are the most common and aggressive form of malignant primary brain tumors
in adults. The standard treatment is surgical resection followed by radiotherapy and …

Functional biomaterials for biomimetic 3D in vitro tumor microenvironment modeling

T Ahmed - In vitro models, 2023 - Springer
The translational potential of promising anticancer medications and treatments may be
enhanced by the creation of 3D in vitro models that can accurately reproduce native tumor …